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eF-site ID
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1h2v-CZ |
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PDB Code
|
1h2v |
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Chain
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C, Z |
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click to enlarge
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Title
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Structure of the human nuclear cap-binding-complex (CBC) |
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Classification
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NUCLEAR PROTEIN |
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Compound
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80 KDA NUCLEAR CAP BINDING PROTEIN |
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Source
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(CB20_HUMAN) |
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Sequence
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C: |
DHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKI
LRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAM
IRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAM
FENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKK
DAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEY
LDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNL
PPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHS
VERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLN
YHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLP
QVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRW
SWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDI
VPPTFSALCPSNPTCIYKYGDESSNSLPGHSVALCLAVAF
KSKATNDEIFSILKDVPNFNPLKIEVFVQTLLHLAAKSFS
HSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQM
IAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEI
LHSTIRKMNKHVLKIQKELEEAKIERLQEKVESAQSEQKN
LFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQ
QIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCAL
QA
|
| Z: |
EKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMG
LDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIR
TDWDAGFKEGRQY
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Description
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Functional site
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|
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1)
|
chain |
Z |
| residue |
43 |
| type |
BINDING |
| sequence |
Y
|
| description |
BINDING => ECO:0000269|PubMed:12374755, ECO:0000269|PubMed:12434151
|
| source |
Swiss-Prot : SWS_FT_FI1
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2)
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chain |
Z |
| residue |
112 |
| type |
BINDING |
| sequence |
R
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
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chain |
Z |
| residue |
123 |
| type |
BINDING |
| sequence |
R
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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4)
|
chain |
C |
| residue |
698 |
| type |
MOD_RES |
| sequence |
K
|
| description |
Phosphoserine => ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI4
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