eF-site ID 1h2u-X PDB Code 1h2u Chain X click to enlarge Title Structure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue m7GpppG Classification NUCLEAR PROTEIN Compound 80 KDA NUCLEAR CAP BINDING PROTEIN Source (CB20_HUMAN) Sequence X:  GLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLY VGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGF CFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGR QYGRGRSGGQVRDEYRQDYDAGRGGYGKL Description Functional site 1) chain X residue 20 type sequence Y description BINDING SITE FOR RESIDUE GDP X1153 source : AC1 2) chain X residue 127 type sequence R description BINDING SITE FOR RESIDUE GDP X1153 source : AC1 3) chain X residue 134 type sequence V description BINDING SITE FOR RESIDUE GDP X1153 source : AC1 4) chain X residue 135 type sequence R description BINDING SITE FOR RESIDUE GDP X1153 source : AC1 5) chain X residue 20 type sequence Y description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 6) chain X residue 22 type sequence D description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 7) chain X residue 43 type sequence Y description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 8) chain X residue 83 type sequence F description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 9) chain X residue 112 type sequence R description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 10) chain X residue 114 type sequence D description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 11) chain X residue 115 type sequence W description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 12) chain X residue 116 type sequence D description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 13) chain X residue 123 type sequence R description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 14) chain X residue 125 type sequence Y description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 15) chain X residue 126 type sequence G description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 16) chain X residue 127 type sequence R description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 17) chain X residue 133 type sequence Q description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 18) chain X residue 134 type sequence V description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 19) chain X residue 135 type sequence R description BINDING SITE FOR RESIDUE 7MG X1154 source : AC2 20) chain X residue 23 type sequence Q description BINDING SITE FOR RESIDUE GDP Y1152 source : AC3 21) chain X residue 25 type sequence F description BINDING SITE FOR RESIDUE GDP Y1152 source : AC3 22) chain X residue 27 type sequence G description BINDING SITE FOR RESIDUE GDP Y1152 source : AC3 23) chain X residue 20 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:12374755, ECO:0000269|PubMed:12434151 source Swiss-Prot : SWS_FT_FI1 24) chain X residue 43 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:12374755, ECO:0000269|PubMed:12434151 source Swiss-Prot : SWS_FT_FI1 25) chain X residue 112 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 26) chain X residue 123 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 27) chain X residue 133 type BINDING sequence Q description source Swiss-Prot : SWS_FT_FI2 28) chain X residue 13 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI4 29) chain X residue 18 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:17525332 source Swiss-Prot : SWS_FT_FI5 30) chain X residue 146 type MOD_RES sequence R description Omega-N-methylarginine => ECO:0007744|PubMed:24129315 source Swiss-Prot : SWS_FT_FI6

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