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eF-site ID
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1h2t-C |
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PDB Code
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1h2t |
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Chain
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C |
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click to enlarge
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Title
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Structure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue m7GpppG |
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Classification
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NUCLEAR PROTEIN |
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Compound
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80 KDA NUCLEAR CAP BINDING PROTEIN |
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Source
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(CB20_HUMAN) |
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Sequence
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C: |
DHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKI
LRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAM
IRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAM
FENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKK
DAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEY
LDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNL
PPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHS
VERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLN
YHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLP
QVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRW
SWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDI
VPPTFSALCPSNPTCIYKYGDESSNSLPGHSVALCLAVAF
KSKATNDEIFSILKDVPNPSFNPLKIEVFVQTLLHLAAKS
FSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHP
QMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVW
EILHSTIRKMNKHVGAQSEQKNLFLVIFQRFIMILTEHLV
RCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLE
NLLFTAELDPHILAVFQQFCALQA
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Description
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Functional site
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1)
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chain |
C |
| residue |
58 |
| type |
|
| sequence |
E
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| description |
BINDING SITE FOR RESIDUE GDP Z1151
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| source |
: AC1
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2)
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chain |
C |
| residue |
746 |
| type |
MOD_RES |
| sequence |
R
|
| description |
Phosphoserine => ECO:0007744|PubMed:23186163
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| source |
Swiss-Prot : SWS_FT_FI4
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