|
|
eF-site ID
|
1gzh-B |
|
PDB Code
|
1gzh |
|
Chain
|
B |
|
click to enlarge
|
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Title
|
Crystal structure of the BRCT domains of human 53BP1 bound to the p53 tumor supressor |
|
Classification
|
GENE REGULATION |
|
Compound
|
CELLULAR TUMOR ANTIGEN P53 |
|
Source
|
null (P53_HUMAN) |
|
|
Sequence
|
B: |
LNKTLFLGYAFLLTMATTSDKLASRSPPFNKQYTESQLRA
GAGYILEDFNTAYQCLLIADQHCRTRKYFLCLASGIPCVS
HVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPREN
PFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSA
HNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWV
IQCLIVGERIGFKQHPKYKHDYVSH
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
1737 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE SO4 B 2972
|
| source |
: AC2
|
|
|
2)
|
chain |
B |
| residue |
1738 |
| type |
|
| sequence |
M
|
| description |
BINDING SITE FOR RESIDUE SO4 B 2972
|
| source |
: AC2
|
|
|
3)
|
chain |
B |
| residue |
1773 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE SO4 B 2972
|
| source |
: AC2
|
|
|
4)
|
chain |
B |
| residue |
1814 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE SO4 B 2972
|
| source |
: AC2
|
|
|
5)
|
chain |
B |
| residue |
1798 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE SO4 D 2970
|
| source |
: AC4
|
|
|
|