eF-site ID 1gqv-A PDB Code 1gqv Chain A click to enlarge Title Atomic Resolution (0.98A) Structure of Eosinophil-Derived Neurotoxin Classification RNASE-2 Compound EOSINOPHIL-DERIVED NEUROTOXIN Source (RNKD_HUMAN) Sequence A:  MKPPQFTWAQWFETQHINMTSQQCTNAMQVINNYQRRCKN QNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVP LIHCNLTTPSPQNISNCRYAQTPANMFYIVACDNRDQRRD PPQYPVVPVHLDRII Description Functional site 1) chain A residue 46 type sequence T description BINDING SITE FOR RESIDUE ACT A 135 source : AC1 2) chain A residue 50 type sequence N description BINDING SITE FOR RESIDUE ACT A 135 source : AC1 3) chain A residue 78 type sequence V description BINDING SITE FOR RESIDUE ACT A 135 source : AC1 4) chain A residue 107 type sequence Y description BINDING SITE FOR RESIDUE ACT A 135 source : AC1 5) chain A residue 15 type ACT_SITE sequence H description Proton acceptor source Swiss-Prot : SWS_FT_FI1 6) chain A residue 129 type ACT_SITE sequence H description Proton donor source Swiss-Prot : SWS_FT_FI2 7) chain A residue 38 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3 8) chain A residue 7 type CARBOHYD sequence W description C-linked (Man) tryptophan => ECO:0000269|PubMed:7947762, ECO:0000269|PubMed:9450956 source Swiss-Prot : SWS_FT_FI5 9) chain A residue 33 type MOD_RES sequence Y description 3'-nitrotyrosine => ECO:0000269|PubMed:18694936 source Swiss-Prot : SWS_FT_FI4 10) chain A residue 37-43 type prosite sequence CKNQNTF description RNASE_PANCREATIC Pancreatic ribonuclease family signature. CKnqNTF source prosite : PS00127 11) chain A residue 17 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine source Swiss-Prot : SWS_FT_FI6 12) chain A residue 59 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine source Swiss-Prot : SWS_FT_FI6 13) chain A residue 65 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine source Swiss-Prot : SWS_FT_FI6 14) chain A residue 84 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine source Swiss-Prot : SWS_FT_FI6 15) chain A residue 92 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine source Swiss-Prot : SWS_FT_FI6

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