eF-site ID 1gpj-A PDB Code 1gpj Chain A click to enlarge Title Glutamyl-tRNA Reductase from Methanopyrus kandleri Classification REDUCTASE Compound Glutamyl-tRNA reductase Source (HEM1_METKA) Sequence A:  MEDLVSVGITHKEAEVEELEKARFESDEAVRDIVESFGLS GSVLLQTSNRVEVYASGARDRAEELGDLIHDDAWVKRGSE AVRHLFRVASGLESMMVGEQEILRQVKKAYDRAARLGTLD EALKIVFRRAINLGKRAREETRISEGAVSIGSAAVELAER ELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVANRT YERAVELARDLGGEAVRFDELVDHLARSDVVVSATAAPHP VIHVDDVREALRKRDRRSPILIIDIANPRDVEEGVENIED VEVRTIDDLRVIARENLERRRKEIPKVEKLIEEELSTVEE ELEKLKERRLVADVAKSLHEIKDRELERALRRLKTVLQDF AEAYTKRLINVLTSAIMELPDEYRRAASRALRRASELNG Description (1)  GLUTAMYL-TRNA REDUCTASE (E.C.1.2.1.-) Functional site 1) chain A residue 23 type sequence R description BINDING SITE FOR RESIDUE GMC A1405 source : AC1 2) chain A residue 25 type sequence E description BINDING SITE FOR RESIDUE GMC A1405 source : AC1 3) chain A residue 48 type sequence S description BINDING SITE FOR RESIDUE GMC A1405 source : AC1 4) chain A residue 101 type sequence E description BINDING SITE FOR RESIDUE GMC A1405 source : AC1 5) chain A residue 47 type sequence T description BINDING SITE FOR RESIDUE GLU A1406 source : AC2 6) chain A residue 49 type sequence N description BINDING SITE FOR RESIDUE GLU A1406 source : AC2 7) chain A residue 50 type sequence R description BINDING SITE FOR RESIDUE GLU A1406 source : AC2 8) chain A residue 94 type sequence S description BINDING SITE FOR RESIDUE GLU A1406 source : AC2 9) chain A residue 99 type sequence E description BINDING SITE FOR RESIDUE GLU A1406 source : AC2 10) chain A residue 101 type sequence E description BINDING SITE FOR RESIDUE GLU A1406 source : AC2 11) chain A residue 102 type sequence I description BINDING SITE FOR RESIDUE GLU A1406 source : AC2 12) chain A residue 105 type sequence Q description BINDING SITE FOR RESIDUE GLU A1406 source : AC2 13) chain A residue 99 type sequence E description BINDING SITE FOR RESIDUE CIT A1407 source : AC3 14) chain A residue 100 type sequence Q description BINDING SITE FOR RESIDUE CIT A1407 source : AC3 15) chain A residue 147 type sequence A description BINDING SITE FOR RESIDUE CIT A1407 source : AC3 16) chain A residue 148 type sequence V description BINDING SITE FOR RESIDUE CIT A1407 source : AC3 17) chain A residue 149 type sequence S description BINDING SITE FOR RESIDUE CIT A1407 source : AC3 18) chain A residue 152 type sequence S description BINDING SITE FOR RESIDUE CIT A1407 source : AC3 19) chain A residue 300 type sequence R description BINDING SITE FOR RESIDUE CIT A1407 source : AC3 20) chain A residue 48 type catalytic sequence S description 804 source MCSA : MCSA1 21) chain A residue 84 type catalytic sequence H description 804 source MCSA : MCSA1 22) chain A residue 48 type ACT_SITE sequence S description Nucleophile source Swiss-Prot : SWS_FT_FI1 23) chain A residue 84-107 type prosite sequence HLFRVASGLESMMVGEQEILRQVK description GLUTR Glutamyl-tRNA reductase signature. HLfrVASGLESmMVGEqEILRQVK source prosite : PS00747 24) chain A residue 47 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI2 25) chain A residue 94 type BINDING sequence S description source Swiss-Prot : SWS_FT_FI2 26) chain A residue 99 type BINDING sequence E description source Swiss-Prot : SWS_FT_FI2 27) chain A residue 105 type BINDING sequence Q description source Swiss-Prot : SWS_FT_FI2 28) chain A residue 174 type BINDING sequence G description BINDING => ECO:0000305 source Swiss-Prot : SWS_FT_FI3 29) chain A residue 84 type SITE sequence H description Important for activity source Swiss-Prot : SWS_FT_FI4

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