eF-site ID 1giu-A PDB Code 1giu Chain A click to enlarge Title A TRICHOSANTHIN(TCS) MUTANT(E85R) COMPLEX STRUCTURE WITH ADENINE Classification HYDROLASE Compound RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN Source Trichosanthes kirilowii (Chinese snake gourd) (Chinese cucumber) (RIPT_TRIKI) Sequence A:  DVSFRLSGATSSSYGVFISNLRKALPNERKLYDIPLLRSS LPGSQRYALIHLTNYADETISVAIDVTNVYIMGYRAGDTS YFFNRASATEAAKYVFKDAMRKVTLPYSGNYERLQTAAGK IRENIPLGLPALDSAITTLFYYNANSAASALMVLIQSTSE AARYKFIEQQIGKRVDKTFLPSLAIISLENSWSALSKQIQ IASTNNGQFESPVVLINAQNQRVTITNVDAGVVTSNIALL LNRNNMA Description Functional site 1) chain A residue 69 type sequence V description BINDING SITE FOR RESIDUE ADE A 300 source : AC1 2) chain A residue 70 type sequence Y description BINDING SITE FOR RESIDUE ADE A 300 source : AC1 3) chain A residue 71 type sequence I description BINDING SITE FOR RESIDUE ADE A 300 source : AC1 4) chain A residue 83 type sequence F description BINDING SITE FOR RESIDUE ADE A 300 source : AC1 5) chain A residue 109 type sequence G description BINDING SITE FOR RESIDUE ADE A 300 source : AC1 6) chain A residue 155 type sequence I description BINDING SITE FOR RESIDUE ADE A 300 source : AC1 7) chain A residue 159 type sequence S description BINDING SITE FOR RESIDUE ADE A 300 source : AC1 8) chain A residue 163 type sequence R description BINDING SITE FOR RESIDUE ADE A 300 source : AC1 9) chain A residue 155-171 type prosite sequence IQSTSEAARYKFIEQQI description SHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. IqSTsEAARYKfIEqqI source prosite : PS00275 10) chain A residue 160 type ACT_SITE sequence E description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI1

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