|
|
eF-site ID
|
1ggr_3-AB |
|
PDB Code
|
1ggr |
|
Model
|
3 |
|
Chain
|
A, B |
|
click to enlarge
|
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Title
|
COMPLEX OF ENZYME IIAGLC AND THE HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR FROM ESCHERICHIA COLI NMR, RESTRAINED REGULARIZED MEAN STRUCTURE |
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Classification
|
TRANSFERASE |
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Compound
|
PTS SYSTEM, GLUCOSE-SPECIFIC IIA COMPONENT |
|
Source
|
Escherichia coli (strain K12) (PTHP_ECOLI) |
|
|
Sequence
|
A: |
TIEIIAPLSGEIVNIEDVPDVVFAEKIVGDGIAIKPTGNK
MVAPVDGTIGKIFETNHAFSIESDSGVELFVHFGIDTVEL
KGEGFKRIAEEGQRVKVGDTVIEFDLPLLEEKAKSTLTPV
VISNMDEIKELIKLSGSVTVGETPVIRIKK
|
| B: |
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGK
SASAKSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKL
MAELE
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
76 |
| type |
BINDING |
| sequence |
A
|
| description |
BINDING => ECO:0000269|PubMed:2657735, ECO:0000269|PubMed:8170944, ECO:0000269|PubMed:9405042, ECO:0000305|PubMed:1961703
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
2)
|
chain |
A |
| residue |
91 |
| type |
BINDING |
| sequence |
F
|
| description |
BINDING => ECO:0000269|PubMed:2657735, ECO:0000269|PubMed:8170944, ECO:0000269|PubMed:9405042, ECO:0000305|PubMed:1961703
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
A |
| residue |
76 |
| type |
SITE |
| sequence |
A
|
| description |
Important for phospho-donor activity => ECO:0000269|PubMed:2657735
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
A |
| residue |
91 |
| type |
MOD_RES |
| sequence |
F
|
| description |
Phosphohistidine; by HPr => ECO:0000269|PubMed:2657735
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
5)
|
chain |
B |
| residue |
315 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Pros-phosphohistidine intermediate => ECO:0000255|PROSITE-ProRule:PRU00681, ECO:0000269|PubMed:2261470
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
B |
| residue |
313-320 |
| type |
prosite |
| sequence |
GLHTRPAA
|
| description |
PTS_HPR_HIS PTS HPR domain histidine phosphorylation site signature. GLHTRPAA
|
| source |
prosite : PS00369
|
|
|
7)
|
chain |
B |
| residue |
339-354 |
| type |
prosite |
| sequence |
GKSASAKSLFKLQTLG
|
| description |
PTS_HPR_SER PTS HPR domain serine phosphorylation site signature. GKsASaKSLFKLQtLG
|
| source |
prosite : PS00589
|
|
|
8)
|
chain |
A |
| residue |
84-96 |
| type |
prosite |
| sequence |
GVELFVHFGIDTV
|
| description |
PTS_EIIA_TYPE_1_HIS PTS EIIA domains phosphorylation site signature 1. GveLFVHFGIdTV
|
| source |
prosite : PS00371
|
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|
|