eF-site ID 1gc3-F PDB Code 1gc3 Chain F click to enlarge Title THERMUS THERMOPHILUS ASPARTATE AMINOTRANSFERASE TETRA MUTANT 2 COMPLEXED WITH TRYPTOPHAN Classification TRANSFERASE Compound ASPARTATE AMINOTRANSFERASE Source (AAT_THETH) Sequence F:  MRGLSRRVQAMKPDAVVAVNAKALELRRQGVDLVALTAGE PDFDTPEHVKEAARRALAQGKTKYAPPAGIPELREALAEK FRRENGLSVTPEETIVTVGGSQALFNLFQAILDPGDEVIV LSPYWVSYPEMVRFAGGVVVEVETLPEEGFVPDPERVRRA ITPRTKALVVNSPNNPTGAVYPKEVLEALARLAVEHDFYL VSDEIYEHLLYEGEHFSPGRVAPEHTLTVNGAAKAFAMTG WRIGYACGPKEVIKAMASVSRQSTTSPDTIAQWATLEALT NQEASRAFVEMAREAYRRRRDLLLEGLTALGLKAVRPSGA FYVLMDTSPIAPDEVRAAERLLEAGVAVVPGTDFAAFGHV RLSYATSEENLRKALERFARVL Description Functional site 1) chain F residue 2516 type sequence V description BINDING SITE FOR RESIDUE TRP E 2914 source : AC6 2) chain F residue 2539 type sequence G description BINDING SITE FOR RESIDUE TRP E 2914 source : AC6 3) chain F residue 2734 type sequence K description BINDING SITE FOR RESIDUE TRP E 2914 source : AC6 4) chain F residue 2822 type sequence Y description BINDING SITE FOR RESIDUE TRP E 2914 source : AC6 5) chain F residue 2861 type sequence R description BINDING SITE FOR RESIDUE TRP E 2914 source : AC6 6) chain F residue 2564 type sequence Y description BINDING SITE FOR RESIDUE PLP E 2413 source : BC4 7) chain F residue 2600 type sequence G description BINDING SITE FOR RESIDUE PLP F 2913 source : BC5 8) chain F residue 2601 type sequence S description BINDING SITE FOR RESIDUE PLP F 2913 source : BC5 9) chain F residue 2625 type sequence W description BINDING SITE FOR RESIDUE PLP F 2913 source : BC5 10) chain F residue 2675 type sequence N description BINDING SITE FOR RESIDUE PLP F 2913 source : BC5 11) chain F residue 2703 type sequence D description BINDING SITE FOR RESIDUE PLP F 2913 source : BC5 12) chain F residue 2706 type sequence Y description BINDING SITE FOR RESIDUE PLP F 2913 source : BC5 13) chain F residue 2734 type sequence K description BINDING SITE FOR RESIDUE PLP F 2913 source : BC5 14) chain F residue 2742 type sequence R description BINDING SITE FOR RESIDUE PLP F 2913 source : BC5 15) chain F residue 2539 type BINDING sequence G description BINDING => ECO:0000250|UniProtKB:P00509 source Swiss-Prot : SWS_FT_FI1 16) chain F residue 2512 type SITE sequence K description Important for prephenate aminotransferase activity => ECO:0000269|PubMed:30771275 source Swiss-Prot : SWS_FT_FI3 17) chain F residue 2734 type MOD_RES sequence K description N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:10029535, ECO:0000269|PubMed:11432784, ECO:0007744|PDB:1B5O, ECO:0007744|PDB:1B5P, ECO:0007744|PDB:5BJ3, ECO:0007744|PDB:5BJ4 source Swiss-Prot : SWS_FT_FI4 18) chain F residue 2625 type BINDING sequence W description BINDING => ECO:0007744|PDB:1GCK source Swiss-Prot : SWS_FT_FI2 19) chain F residue 2675 type BINDING sequence N description BINDING => ECO:0007744|PDB:1GCK source Swiss-Prot : SWS_FT_FI2 20) chain F residue 2861 type BINDING sequence R description BINDING => ECO:0007744|PDB:1GCK source Swiss-Prot : SWS_FT_FI2

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