eF-site ID 1gc3-E PDB Code 1gc3 Chain E click to enlarge Title THERMUS THERMOPHILUS ASPARTATE AMINOTRANSFERASE TETRA MUTANT 2 COMPLEXED WITH TRYPTOPHAN Classification TRANSFERASE Compound ASPARTATE AMINOTRANSFERASE Source (AAT_THETH) Sequence E:  MRGLSRRVQAMKPDAVVAVNAKALELRRQGVDLVALTAGE PDFDTPEHVKEAARRALAQGKTKYAPPAGIPELREALAEK FRRENGLSVTPEETIVTVGGSQALFNLFQAILDPGDEVIV LSPYWVSYPEMVRFAGGVVVEVETLPEEGFVPDPERVRRA ITPRTKALVVNSPNNPTGAVYPKEVLEALARLAVEHDFYL VSDEIYEHLLYEGEHFSPGRVAPEHTLTVNGAAKAFAMTG WRIGYACGPKEVIKAMASVSRQSTTSPDTIAQWATLEALT NQEASRAFVEMAREAYRRRRDLLLEGLTALGLKAVRPSGA FYVLMDTSPIAPDEVRAAERLLEAGVAVVPGTDFAAFGHV RLSYATSEENLRKALERFARVL Description Functional site 1) chain E residue 2039 type sequence G description BINDING SITE FOR RESIDUE TRP E 2414 source : AC5 2) chain E residue 2322 type sequence Y description BINDING SITE FOR RESIDUE TRP E 2414 source : AC5 3) chain E residue 2361 type sequence R description BINDING SITE FOR RESIDUE TRP E 2414 source : AC5 4) chain E residue 2064 type sequence Y description BINDING SITE FOR RESIDUE TRP E 2914 source : AC6 5) chain E residue 2099 type sequence G description BINDING SITE FOR RESIDUE PLP E 2413 source : BC4 6) chain E residue 2100 type sequence G description BINDING SITE FOR RESIDUE PLP E 2413 source : BC4 7) chain E residue 2101 type sequence S description BINDING SITE FOR RESIDUE PLP E 2413 source : BC4 8) chain E residue 2125 type sequence W description BINDING SITE FOR RESIDUE PLP E 2413 source : BC4 9) chain E residue 2175 type sequence N description BINDING SITE FOR RESIDUE PLP E 2413 source : BC4 10) chain E residue 2203 type sequence D description BINDING SITE FOR RESIDUE PLP E 2413 source : BC4 11) chain E residue 2206 type sequence Y description BINDING SITE FOR RESIDUE PLP E 2413 source : BC4 12) chain E residue 2233 type sequence A description BINDING SITE FOR RESIDUE PLP E 2413 source : BC4 13) chain E residue 2242 type sequence R description BINDING SITE FOR RESIDUE PLP E 2413 source : BC4 14) chain E residue 2322 type sequence Y description BINDING SITE FOR RESIDUE PLP E 2413 source : BC4 15) chain E residue 2064 type sequence Y description BINDING SITE FOR RESIDUE PLP F 2913 source : BC5 16) chain E residue 2039 type BINDING sequence G description BINDING => ECO:0000250|UniProtKB:P00509 source Swiss-Prot : SWS_FT_FI1 17) chain E residue 2125 type BINDING sequence W description BINDING => ECO:0007744|PDB:1GCK source Swiss-Prot : SWS_FT_FI2 18) chain E residue 2175 type BINDING sequence N description BINDING => ECO:0007744|PDB:1GCK source Swiss-Prot : SWS_FT_FI2 19) chain E residue 2361 type BINDING sequence R description BINDING => ECO:0007744|PDB:1GCK source Swiss-Prot : SWS_FT_FI2 20) chain E residue 2012 type SITE sequence K description Important for prephenate aminotransferase activity => ECO:0000269|PubMed:30771275 source Swiss-Prot : SWS_FT_FI3 21) chain E residue 2234 type MOD_RES sequence K description N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:10029535, ECO:0000269|PubMed:11432784, ECO:0007744|PDB:1B5O, ECO:0007744|PDB:1B5P, ECO:0007744|PDB:5BJ3, ECO:0007744|PDB:5BJ4 source Swiss-Prot : SWS_FT_FI4

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