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eF-site ID
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1g65-O |
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PDB Code
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1g65 |
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Chain
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O |
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click to enlarge
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Title
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Crystal structure of epoxomicin:20s proteasome reveals a molecular basis for selectivity of alpha,beta-epoxyketone proteasome inhibitors |
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Classification
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HYDROLASE/HYDROLASE inhibitor |
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Compound
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Proteasome component Y7 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
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O: |
MTDRYSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKAT
NGVVIATEKKSSSPLAMSETLSKVSLLTPDIGAVYSGMGP
DYRVLVDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQE
ATQSGGVRPFGVSLLIAGHDEFNGFSLYQVDPSGSYFPWK
ATAIGKGSVAAKTFLEKRWNDELELEDAIHIALLTLKESV
EGEFNGDTIELAIIGDENPDLLGYTGIPTDKGPRFRKLTS
QEINDRLEAL
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Description
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