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eF-site ID
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1g65-D |
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PDB Code
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1g65 |
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Chain
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D |
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click to enlarge
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Title
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Crystal structure of epoxomicin:20s proteasome reveals a molecular basis for selectivity of alpha,beta-epoxyketone proteasome inhibitors |
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Classification
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HYDROLASE/HYDROLASE inhibitor |
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Compound
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Proteasome component Y7 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
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D: |
DRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVL
GVEKRATSPLLESDSIEKIVEIDRHIGCAMSGLTADARSM
IEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGAS
GEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYN
AKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVM
EEKLDENNAQLSCITKQDGFKIYDNEKTAELIKELKEKEA
AE
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Description
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Functional site
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|
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1)
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chain |
D |
| residue |
105 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE MG D 301
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| source |
: AC1
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