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eF-site ID
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1fyt-A |
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PDB Code
|
1fyt |
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Chain
|
A |
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click to enlarge
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Title
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CRYSTAL STRUCTURE OF A COMPLEX OF A HUMAN ALPHA/BETA-T CELL RECEPTOR, INFLUENZA HA ANTIGEN PEPTIDE, AND MHC CLASS II MOLECULE, HLA-DR1 |
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Classification
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IMMUNE SYSTEM |
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Compound
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HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN |
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Source
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(TCB_HUMAN) |
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Sequence
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A: |
KEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKET
VWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTP
ITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTW
LRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVY
DCRVEHWGLDEPLLKHWEFD
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Description
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Functional site
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|
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1)
|
chain |
A |
| residue |
52 |
| type |
CARBOHYD |
| sequence |
A
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498
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| source |
Swiss-Prot : SWS_FT_FI2
|
|
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2)
|
chain |
A |
| residue |
55 |
| type |
SITE |
| sequence |
E
|
| description |
Pathogen-derived peptide antigen => ECO:0000269|PubMed:23260142, ECO:0007744|PDB:4GBX
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| source |
Swiss-Prot : SWS_FT_FI5
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|
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3)
|
chain |
A |
| residue |
62 |
| type |
SITE |
| sequence |
N
|
| description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
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4)
|
chain |
A |
| residue |
69 |
| type |
SITE |
| sequence |
N
|
| description |
Pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX
|
| source |
Swiss-Prot : SWS_FT_FI7
|
|
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5)
|
chain |
A |
| residue |
76 |
| type |
SITE |
| sequence |
R
|
| description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX
|
| source |
Swiss-Prot : SWS_FT_FI8
|
|
|
6)
|
chain |
A |
| residue |
78 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400
|
| source |
Swiss-Prot : SWS_FT_FI9
|
|
|
7)
|
chain |
A |
| residue |
118 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400
|
| source |
Swiss-Prot : SWS_FT_FI9
|
|
|
8)
|
chain |
A |
| residue |
53 |
| type |
SITE |
| sequence |
S
|
| description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
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9)
|
chain |
A |
| residue |
161-167 |
| type |
prosite |
| sequence |
YDCRVEH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YDCRVEH
|
| source |
prosite : PS00290
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