eF-site ID 1fv1-B PDB Code 1fv1 Chain B click to enlarge Title STRUCTURAL BASIS FOR THE BINDING OF AN IMMUNODOMINANT PEPTIDE FROM MYELIN BASIC PROTEIN IN DIFFERENT REGISTERS BY TWO HLA-DR2 ALLELES Classification IMMUNE SYSTEM Compound MAJOR HISTOCOMPATIBILITY COMPLEX ALPHA CHAIN Source Homo sapiens (Human) (MBP_HUMAN) Sequence B:  GDTRPRFLQQDKYECHFFNGTERVRFLHRDIYNQEEDLRF DSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCR HNYGVGESFTVQRRVEPKVTVYPARTQTLQHHNLLVCSVN GFYPGSIEVRWFRNSQEEKAGVVSTGLIQNGDWTFQTLVM LETVPRSGEVYTCQVEHPSVTSPLTVEWRA Description (1)  MAJOR HISTOCOMPATIBILITY COMPLEX ALPHA CHAIN/MAJOR HISTOCOMPATIBILITY COMPLEX BETA CHAIN/MYELIN BASIC PROTEIN Functional site 1) chain B residue 29 type sequence R description BINDING SITE FOR RESIDUE SO4 B 191 source : AC3 2) chain B residue 39 type sequence R description BINDING SITE FOR RESIDUE SO4 B 191 source : AC3 3) chain B residue 48 type sequence R description BINDING SITE FOR RESIDUE GOL D 183 source : AC4 4) chain B residue 94 type sequence R description BINDING SITE FOR RESIDUE GOL B 192 source : AC5 5) chain B residue 179 type sequence S description BINDING SITE FOR RESIDUE GOL B 192 source : AC5 6) chain B residue 171-177 type prosite sequence YTCQVEH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCQVEH source prosite : PS00290

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