eF-site ID 1fqk-A PDB Code 1fqk Chain A click to enlarge Title CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)] Classification SIGNALING PROTEIN Compound Guanine nucleotide-binding protein G(t) subunit alpha-1,Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(t) subunit alpha-1 Source null (RGS9_BOVIN) Sequence A:  RTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIA IIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMA DTIEEGTMPKEMSDIIQRLWKDSGIQACFDRASEYQLNDS AGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSF KDLNFRMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYD LVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKK DLFEEKIKKSPLTICYPEYAGSNTYEEAGNYIKVQFLELN MRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLK Description Functional site 1) chain A residue 43 type sequence S description BINDING SITE FOR RESIDUE MG A 352 source : AC1 2) chain A residue 177 type sequence T description BINDING SITE FOR RESIDUE MG A 352 source : AC1 3) chain A residue 37 type sequence A description BINDING SITE FOR RESIDUE ALF A 362 source : AC2 4) chain A residue 38 type sequence G description BINDING SITE FOR RESIDUE ALF A 362 source : AC2 5) chain A residue 39 type sequence E description BINDING SITE FOR RESIDUE ALF A 362 source : AC2 6) chain A residue 42 type sequence K description BINDING SITE FOR RESIDUE ALF A 362 source : AC2 7) chain A residue 174 type sequence R description BINDING SITE FOR RESIDUE ALF A 362 source : AC2 8) chain A residue 175 type sequence V description BINDING SITE FOR RESIDUE ALF A 362 source : AC2 9) chain A residue 176 type sequence K description BINDING SITE FOR RESIDUE ALF A 362 source : AC2 10) chain A residue 177 type sequence T description BINDING SITE FOR RESIDUE ALF A 362 source : AC2 11) chain A residue 199 type sequence G description BINDING SITE FOR RESIDUE ALF A 362 source : AC2 12) chain A residue 200 type sequence Q description BINDING SITE FOR RESIDUE ALF A 362 source : AC2 13) chain A residue 38 type sequence G description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 14) chain A residue 39 type sequence E description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 15) chain A residue 40 type sequence S description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 16) chain A residue 41 type sequence G description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 17) chain A residue 42 type sequence K description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 18) chain A residue 43 type sequence S description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 19) chain A residue 44 type sequence T description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 20) chain A residue 146 type sequence D description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 21) chain A residue 147 type sequence S description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 22) chain A residue 171 type sequence L description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 23) chain A residue 172 type sequence R description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 24) chain A residue 173 type sequence S description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 25) chain A residue 174 type sequence R description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 26) chain A residue 265 type sequence N description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 27) chain A residue 266 type sequence K description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 28) chain A residue 268 type sequence D description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 29) chain A residue 269 type sequence L description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 30) chain A residue 321 type sequence C description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 31) chain A residue 322 type sequence A description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 32) chain A residue 323 type sequence T description BINDING SITE FOR RESIDUE GDP A 360 source : AC5 33) chain A residue 43 type BINDING sequence S description BINDING => ECO:0000255|PROSITE-ProRule:PRU01230 source Swiss-Prot : SWS_FT_FI2 34) chain A residue 177 type BINDING sequence T description BINDING => ECO:0000255|PROSITE-ProRule:PRU01230 source Swiss-Prot : SWS_FT_FI2 35) chain A residue 199 type BINDING sequence G description BINDING => ECO:0000269|PubMed:8259210, ECO:0007744|PDB:1TND source Swiss-Prot : SWS_FT_FI3 36) chain A residue 322 type BINDING sequence A description BINDING => ECO:0000269|PubMed:8259210, ECO:0007744|PDB:1TND source Swiss-Prot : SWS_FT_FI3 37) chain A residue 36 type BINDING sequence G description BINDING => ECO:0000269|PubMed:7969474, ECO:0000269|PubMed:8208289, ECO:0000269|PubMed:8259210, ECO:0007744|PDB:1FQJ, ECO:0007744|PDB:1FQK, ECO:0007744|PDB:1GOT, ECO:0007744|PDB:1TAD, ECO:0007744|PDB:1TAG, ECO:0007744|PDB:1TND, ECO:0007744|PDB:3V00 source Swiss-Prot : SWS_FT_FI1 38) chain A residue 146 type BINDING sequence D description BINDING => ECO:0000269|PubMed:7969474, ECO:0000269|PubMed:8208289, ECO:0000269|PubMed:8259210, ECO:0007744|PDB:1FQJ, ECO:0007744|PDB:1FQK, ECO:0007744|PDB:1GOT, ECO:0007744|PDB:1TAD, ECO:0007744|PDB:1TAG, ECO:0007744|PDB:1TND, ECO:0007744|PDB:3V00 source Swiss-Prot : SWS_FT_FI1 39) chain A residue 171 type BINDING sequence L description BINDING => ECO:0000269|PubMed:7969474, ECO:0000269|PubMed:8208289, ECO:0000269|PubMed:8259210, ECO:0007744|PDB:1FQJ, ECO:0007744|PDB:1FQK, ECO:0007744|PDB:1GOT, ECO:0007744|PDB:1TAD, ECO:0007744|PDB:1TAG, ECO:0007744|PDB:1TND, ECO:0007744|PDB:3V00 source Swiss-Prot : SWS_FT_FI1 40) chain A residue 142 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000250|UniProtKB:P11488 source Swiss-Prot : SWS_FT_FI4 41) chain A residue 265 type BINDING sequence N description BINDING => ECO:0007744|PDB:1AS0, ECO:0007744|PDB:1BH2, ECO:0007744|PDB:1GIA, ECO:0007744|PDB:1GIL, ECO:0007744|PDB:3FFA, ECO:0007744|PDB:4N0D, ECO:0007744|PDB:4PAO, ECO:0007744|PDB:4PAQ source Swiss-Prot : SWS_FT_FI5

Display surface Download Links