eF-site ID 1fm9-A PDB Code 1fm9 Chain A click to enlarge Title THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND GI262570 AND CO-ACTIVATOR PEPTIDES. Classification TRANSCRIPTION Compound RETINOIC ACID RECEPTOR RXR-ALPHA Source Homo sapiens (Human) (O43793) Sequence A:  NEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVT NICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWN ELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIF DRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNP AEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALR SIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP Description Functional site 1) chain A residue 271 type sequence A description BINDING SITE FOR RESIDUE 9CR A 201 source : AC2 2) chain A residue 275 type sequence Q description BINDING SITE FOR RESIDUE 9CR A 201 source : AC2 3) chain A residue 305 type sequence W description BINDING SITE FOR RESIDUE 9CR A 201 source : AC2 4) chain A residue 313 type sequence F description BINDING SITE FOR RESIDUE 9CR A 201 source : AC2 5) chain A residue 316 type sequence R description BINDING SITE FOR RESIDUE 9CR A 201 source : AC2 6) chain A residue 326 type sequence L description BINDING SITE FOR RESIDUE 9CR A 201 source : AC2 7) chain A residue 327 type sequence A description BINDING SITE FOR RESIDUE 9CR A 201 source : AC2 8) chain A residue 432 type sequence C description BINDING SITE FOR RESIDUE 9CR A 201 source : AC2 9) chain A residue 435 type sequence H description BINDING SITE FOR RESIDUE 9CR A 201 source : AC2 10) chain A residue 436 type sequence L description BINDING SITE FOR RESIDUE 9CR A 201 source : AC2 11) chain A residue 260 type MOD_RES sequence S description Phosphoserine; by MAPK8 and MAPK9 => ECO:0000250|UniProtKB:P28700 source Swiss-Prot : SWS_FT_FI3

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