eF-site ID 1fe8-ABCHIJLMN PDB Code 1fe8 Chain A, B, C, H, I, J, L, M, N click to enlarge Title CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR A3 DOMAIN IN COMPLEX WITH A FAB FRAGMENT OF IGG RU5 THAT INHIBITS COLLAGEN BINDING Classification IMMUNE SYSTEM Compound VON WILLEBRAND FACTOR Source ORGANISM_COMMON: house mouse; ORGANISM_SCIENTIFIC: Mus musculus; Sequence A:  PDCSQPLDVILLLDGSSSFPASYFDEXKSFAKAFISKANI GPRLTQVSVLQYGSITTIDVPWNVVPEKAHLLSLVDVXQR EGGPSQIGDALGFAVRYLTSEXHGARPGASKAVVILVTDV SVDSVDAAADAARSNRVTVFPIGIGDRYDAAQLRILAGPA GDSNVVKLQRIEDLPTXVTLGNSFLHKLCS B:  PDCSQPLDVILLLDGSSSFPASYFDEXKSFAKAFISKANI GPRLTQVSVLQYGSITTIDVPWNVVPEKAHLLSLVDVXQR EGGPSQIGDALGFAVRYLTSEXHGARPGASKAVVILVTDV SVDSVDAAADAARSNRVTVFPIGIGDRYDAAQLRILAGPA GDSNVVKLQRIEDLPTXVTLGNSFLHKLCS C:  APDCSQPLDVILLLDGSSSFPASYFDEXKSFAKAFISKAN IGPRLTQVSVLQYGSITTIDVPWNVVPEKAHLLSLVDVXQ REGGPSQIGDALGFAVRYLTSEXHGARPGASKAVVILVTD VSVDSVDAAADAARSNRVTVFPIGIGDRYDAAQLRILAGP AGDSNVVKLQRIEDLPTXVTLGNSFLHKLCS H:  DVKLVQSGPGLVAPSQSLSITCTVSGFSLTTYGVSWVRQP PGKGLEWLGVIWGDGNTTYHSALISRLSISKDNSRSQVFL KLNSLHTDDTATYYCAGNYYGMDYWGQGTSVTVSSAETTA PSVYKLEPVSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVH TFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASST KVDKKIEPRG I:  DVKLVQSGPGLVAPSQSLSITCTVSGFSLTTYGVSWVRQP PGKGLEWLGVIWGDGNTTYHSALISRLSISKDNSRSQVFL KLNSLHTDDTATYYCAGNYYGMDYWGQGTSVTVSSAETTA PSVYKLEPVSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVH TFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASST KVDKKIEPRG J:  DVKLVQSGPGLVAPSQSLSITCTVSGFSLTTYGVSWVRQP PGKGLEWLGVIWGDGNTTYHSALISRLSISKDNSRSQVFL KLNSLHTDDTATYYCAGNYYGMDYWGQGTSVTVSSAETTA PSVYKLEPVSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVH TFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASST KVDKKIEPRG L:  DIAMTQTTSSLSASLGQKVTISCRASQDIGNYLNWYQQKP DGTVRLLIYYTSRLHSGVPSRFSGSGSGTDYSLTISNLES EDIATYFCQNGGTNPWTFGGGTKLEVKRADAAPTTSIFPP SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT STSPIVKSFNR M:  DIAMTQTTSSLSASLGQKVTISCRASQDIGNYLNWYQQKP DGTVRLLIYYTSRLHSGVPSRFSGSGSGTDYSLTISNLES EDIATYFCQNGGTNPWTFGGGTKLEVKRADAAPTTSIFPP SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT STSPIVKSFNR N:  DIAMTQTTSSLSASLGQKVTISCRASQDIGNYLNWYQQKP DGTVRLLIYYTSRLHSGVPSRFSGSGSGTDYSLTISNLES EDIATYFCQNGGTNPWTFGGGTKLEVKRADAAPTTSIFPP SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT STSPIVKSFNR Description (1)  VON WILLEBRAND FACTOR Functional site 1) chain L residue 192-198 type prosite sequence YTCEATH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH source prosite : PS00290

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