|
|
eF-site ID
|
1fcu-A |
|
PDB Code
|
1fcu |
|
Chain
|
A |
|
click to enlarge
|
|
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Title
|
CRYSTAL STRUCTURE (TRIGONAL) OF BEE VENOM HYALURONIDASE |
|
Classification
|
HYDROLASE |
|
Compound
|
HYALURONOGLUCOSAMINIDASE |
|
Source
|
Apis mellifera (Honeybee) (HUGA_APIME) |
|
|
Sequence
|
A: |
EFNVYWNVPTFMCHKYGLRFEEVSEKYGILQNWMDKFRGE
EIAILYDPGMFPALLKDPNGNVVARNGGVPQLGNLTKHLQ
VFRDHLINQIPDKSFPGVGVIDFESWRPIFRQNWASLQPY
KKLSVEVVRREHPFWDDQRVEQEAKRRFEKYGQLFMEETL
KAAKRMRPAANWGYYAYPYCYNLTPNQPSAQCEATTMQEN
DKMSWLFESEDVLLPSVYLRWNLTSGERVGLVGGRVKEAL
RIARQMTTSRKKVLPYYWYKYQDRRDTDLSRADLEATLRK
ITDLGADGFIIWGSSDDINTKAKCLQFREYLNNELGPAVK
RIAL
|
|
|
Description
|
(1) |
HYALURONIDASE (3.2.1.35)
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
111 |
| type |
catalytic |
| sequence |
D
|
| description |
616
|
| source |
MCSA : MCSA1
|
|
|
2)
|
chain |
A |
| residue |
113 |
| type |
catalytic |
| sequence |
E
|
| description |
616
|
| source |
MCSA : MCSA1
|
|
|
3)
|
chain |
A |
| residue |
184 |
| type |
catalytic |
| sequence |
Y
|
| description |
616
|
| source |
MCSA : MCSA1
|
|
|
4)
|
chain |
A |
| residue |
227 |
| type |
catalytic |
| sequence |
Y
|
| description |
616
|
| source |
MCSA : MCSA1
|
|
|
5)
|
chain |
A |
| residue |
301 |
| type |
catalytic |
| sequence |
W
|
| description |
616
|
| source |
MCSA : MCSA1
|
|
|
6)
|
chain |
A |
| residue |
113 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
Proton donor => ECO:0000305|PubMed:11080624
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
A |
| residue |
83 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
8)
|
chain |
A |
| residue |
231 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:10998264
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|