eF-site ID 1f66-ABCDEFGH PDB Code 1f66 Chain A, B, C, D, E, F, G, H click to enlarge Title 2.6 A CRYSTAL STRUCTURE OF A NUCLEOSOME CORE PARTICLE CONTAINING THE VARIANT HISTONE H2A.Z Classification STRUCTURAL PROTEIN/DNA Compound PALINDROMIC 146 BASE PAIR DNA FRAGMENT Source Mus musculus (Mouse) (1F66) Sequence A:  KKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIA QDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAK RVTIMPKDIQLARRIRGERA B:  RDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFL ENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG C:  AVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSA AILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEE LDSLIKATIAGGGVIPHIHKSLI D:  KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVF ERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHA VSEGTKAVTKYTSAK E:  GEVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVR EIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAI HAKRVTIMPKDIQLARRIRGERA F:  RHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRG VLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRT LYGFGG G:  AVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSA AILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEE LDSLIKATIAGGGVIPHIHKSLIGKKG H:  KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVF ERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHA VSEGTKAVTKYTSAK Description Functional site 1) chain D residue 1245 type sequence V description BINDING SITE FOR RESIDUE MN E 1001 source : AC1 2) chain E residue 677 type sequence D description BINDING SITE FOR RESIDUE MN E 1001 source : AC1 3) chain C residue 912 type sequence H description BINDING SITE FOR RESIDUE MN C 1014 source : BC4 4) chain C residue 914 type sequence H description BINDING SITE FOR RESIDUE MN C 1014 source : BC4 5) chain G residue 1112 type sequence H description BINDING SITE FOR RESIDUE MN G 1128 source : BC5 6) chain G residue 1114 type sequence H description BINDING SITE FOR RESIDUE MN G 1128 source : BC5 7) chain C residue 823-829 type prosite sequence AGLQFPV description HISTONE_H2A Histone H2A signature. AGLqFPV source prosite : PS00046 8) chain D residue 1289-1311 type prosite sequence REIQTAVRLLLPGELAKHAVSEG description HISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG source prosite : PS00357 9) chain A residue 466-474 type prosite sequence PFQRLVREI description HISTONE_H3_2 Histone H3 signature 2. PFqRLVREI source prosite : PS00959 10) chain E residue 664 type MOD_RES sequence K description N6-methyllysine; alternate => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI10 11) chain A residue 436 type MOD_RES sequence K description N6-methyllysine; alternate => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI10 12) chain A residue 464 type MOD_RES sequence K description N6-methyllysine; alternate => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI10 13) chain E residue 636 type MOD_RES sequence K description N6-methyllysine; alternate => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI10 14) chain A residue 437 type MOD_RES sequence K description N6-methyllysine => ECO:0000250|UniProtKB:P68431 source Swiss-Prot : SWS_FT_FI13 15) chain E residue 637 type MOD_RES sequence K description N6-methyllysine => ECO:0000250|UniProtKB:P68431 source Swiss-Prot : SWS_FT_FI13 16) chain A residue 441 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI14 17) chain E residue 641 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI14 18) chain A residue 456 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P84228 source Swiss-Prot : SWS_FT_FI15 19) chain A residue 479 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P84228 source Swiss-Prot : SWS_FT_FI15 20) chain E residue 656 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P84228 source Swiss-Prot : SWS_FT_FI15 21) chain E residue 679 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P84228 source Swiss-Prot : SWS_FT_FI15 22) chain F residue 220 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P84228 source Swiss-Prot : SWS_FT_FI15 23) chain F residue 259 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P84228 source Swiss-Prot : SWS_FT_FI15 24) chain F residue 279 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P84228 source Swiss-Prot : SWS_FT_FI15 25) chain A residue 457 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI16 26) chain E residue 657 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI16 27) chain F residue 291 type MOD_RES sequence K description Phosphoserine => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI16 28) chain A residue 480 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI17 29) chain A residue 507 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI17 30) chain E residue 680 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI17 31) chain E residue 707 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI17 32) chain A residue 486 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P84243 source Swiss-Prot : SWS_FT_FI18 33) chain E residue 686 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P84243 source Swiss-Prot : SWS_FT_FI18 34) chain A residue 515 type MOD_RES sequence K description N6-glutaryllysine; alternate => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI19 35) chain E residue 715 type MOD_RES sequence K description N6-glutaryllysine; alternate => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI19 36) chain A residue 522 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI20 37) chain E residue 722 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI20 38) chain A residue 510 type LIPID sequence C description S-palmitoyl cysteine => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI21 39) chain E residue 710 type LIPID sequence C description S-palmitoyl cysteine => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI21 40) chain H residue 1518 type MOD_RES sequence Y description 5-glutamyl serotonin; alternate => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI4 41) chain F residue 244 type MOD_RES sequence K description Phosphothreonine; by PKC => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI5 42) chain B residue 79 type MOD_RES sequence K description Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI8 43) chain F residue 231 type MOD_RES sequence K description Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI8 44) chain F residue 277 type MOD_RES sequence K description Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI8 45) chain F residue 279 type MOD_RES sequence K description Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000250|UniProtKB:Q71DI3 source Swiss-Prot : SWS_FT_FI8

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