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eF-site ID
|
1f45-AB |
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PDB Code
|
1f45 |
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Chain
|
A, B |
|
click to enlarge
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Title
|
HUMAN INTERLEUKIN-12 |
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Classification
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CYTOKINE/CYTOKINE |
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Compound
|
INTERLEUKIN-12 BETA CHAIN |
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Source
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(I12A_HUMAN) |
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Sequence
|
A: |
IWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITWTL
DQSSEVLGSGKTLTIQVKEFGDAGQYTCSHSLLLLHKKED
GIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTIS
TDLTFSVKSSRGSSDPQGVTCGAATLSAEEYEYSVECQED
SACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPD
PPKNLQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQ
VQKDRVFTDKTSATVICRSISVRAQDRYYSSSWSEWASVP
CS
|
| B: |
QNLLRAVSNMLQKARQTLEFYPCSTVEACLPLELTKNESC
TSFITNGSSFMMALCLSSIYEDLKMYQVEFKTMNAKLLMD
PKRQIFLDQNMLAVIDELMQALYKTKIKLCILLHAFRIRA
VTIDRVMSYLNAS
|
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Description
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Functional site
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|
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1)
|
chain |
B |
| residue |
71 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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2)
|
chain |
B |
| residue |
84 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
200 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10899108
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
A |
| residue |
211-253 |
| type |
prosite |
| sequence |
IKPDPPKNLQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLT
FCV
|
| description |
HEMATOPO_REC_L_F3 Long hematopoietin receptor, soluble alpha chains family signature. IkPDPPknLqlkplknsrq.VevsWeyPdTWstphsyFsLtFcV
|
| source |
prosite : PS01354
|
|
|
5)
|
chain |
A |
| residue |
297 |
| type |
CARBOHYD |
| sequence |
W
|
| description |
C-linked (Man) tryptophan => ECO:0000269|PubMed:10207176
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
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|