|
|
eF-site ID
|
1ewn-A |
|
PDB Code
|
1ewn |
|
Chain
|
A |
|
click to enlarge
|
|
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Title
|
CRYSTAL STRUCTURE OF THE HUMAN AAG DNA REPAIR GLYCOSYLASE COMPLEXED WITH 1,N6-ETHENOADENINE-DNA |
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Classification
|
hydrolase/DNA |
|
Compound
|
DNA (5'-D(*GP*AP*CP*AP*TP*GP*(EDA)P*TP*TP*GP*CP*C)-3') |
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Source
|
(1EWN) |
|
|
Sequence
|
A: |
HLTRLGLEFFDQPAVPLARAFLGQVLVRRLPNGTELRGRI
VETQAYLGPEDEAAHSRGGRQTPRNRGMFMKPGTLYVYII
YGMYFCMNISSQGDGACVLLRALEPLEGLETMRQLRSTVL
KDRELCSGPSKLCQALAINKSFDQRDLAQDEAVWLERGPA
VVAAARVGVGHAGEWARKPLRFYVRGSPWVSVVDRVAEQD
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
149 |
| type |
|
| sequence |
M
|
| description |
BINDING SITE FOR RESIDUE NA A 501
|
| source |
: AC1
|
|
|
2)
|
chain |
A |
| residue |
171 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE NA A 501
|
| source |
: AC1
|
|
|
3)
|
chain |
A |
| residue |
172 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE NA A 501
|
| source |
: AC1
|
|
|
4)
|
chain |
A |
| residue |
174 |
| type |
|
| sequence |
G
|
| description |
BINDING SITE FOR RESIDUE NA A 501
|
| source |
: AC1
|
|
|
5)
|
chain |
A |
| residue |
177 |
| type |
|
| sequence |
A
|
| description |
BINDING SITE FOR RESIDUE NA A 501
|
| source |
: AC1
|
|
|
|