eF-site ID 1ev6-ABCDEFGHIJKL PDB Code 1ev6 Chain A, B, C, D, E, F, G, H, I, J, K, L click to enlarge Title Structure of the monoclinic form of the M-cresol/insulin R6 hexamer Classification HORMONE/GROWTH FACTOR Compound INSULIN Source (INS_HUMAN) Sequence A:  GIVEQCCTSICSLYQLENYCN B:  FVNQHLCGSHLVEALYLVCGERGFFYTPK C:  GIVEQCCTSICSLYQLENYCN D:  FVNQHLCGSHLVEALYLVCGERGFFYTPK E:  GIVEQCCTSICSLYQLENYCN F:  FVNQHLCGSHLVEALYLVCGERGFFYTPKT G:  GIVEQCCTSICSLYQLENYCN H:  FVNQHLCGSHLVEALYLVCGERGFFYTPK I:  GIVEQCCTSICSLYQLENYCN J:  FVNQHLCGSHLVEALYLVCGERGFFYTPK K:  GIVEQCCTSICSLYQLENYCN L:  FVNQHLCGSHLVEALYLVCGERGFFYTPK Description (1)  INSULIN Functional site 1) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN B 301 source : AC1 2) chain F residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN B 301 source : AC1 3) chain J residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN B 301 source : AC1 4) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN D 302 source : AC2 5) chain H residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN D 302 source : AC2 6) chain L residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN D 302 source : AC2 7) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE CL B 303 source : AC3 8) chain F residue 10 type sequence H description BINDING SITE FOR RESIDUE CL B 303 source : AC3 9) chain J residue 10 type sequence H description BINDING SITE FOR RESIDUE CL B 303 source : AC3 10) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE CL D 304 source : AC4 11) chain H residue 10 type sequence H description BINDING SITE FOR RESIDUE CL D 304 source : AC4 12) chain L residue 10 type sequence H description BINDING SITE FOR RESIDUE CL D 304 source : AC4 13) chain C residue 21 type sequence N description BINDING SITE FOR RESIDUE NA C 305 source : AC5 14) chain A residue 6 type sequence C description BINDING SITE FOR RESIDUE CRS A 306 source : AC6 15) chain A residue 10 type sequence I description BINDING SITE FOR RESIDUE CRS A 306 source : AC6 16) chain A residue 11 type sequence C description BINDING SITE FOR RESIDUE CRS A 306 source : AC6 17) chain B residue 11 type sequence L description BINDING SITE FOR RESIDUE CRS A 306 source : AC6 18) chain B residue 14 type sequence A description BINDING SITE FOR RESIDUE CRS A 306 source : AC6 19) chain F residue 5 type sequence H description BINDING SITE FOR RESIDUE CRS A 306 source : AC6 20) chain C residue 6 type sequence C description BINDING SITE FOR RESIDUE CRS C 307 source : AC7 21) chain C residue 10 type sequence I description BINDING SITE FOR RESIDUE CRS C 307 source : AC7 22) chain C residue 11 type sequence C description BINDING SITE FOR RESIDUE CRS C 307 source : AC7 23) chain D residue 11 type sequence L description BINDING SITE FOR RESIDUE CRS C 307 source : AC7 24) chain D residue 14 type sequence A description BINDING SITE FOR RESIDUE CRS C 307 source : AC7 25) chain J residue 17 type sequence L description BINDING SITE FOR RESIDUE CRS C 307 source : AC7 26) chain L residue 5 type sequence H description BINDING SITE FOR RESIDUE CRS C 307 source : AC7 27) chain E residue 6 type sequence C description BINDING SITE FOR RESIDUE CRS E 308 source : AC8 28) chain E residue 10 type sequence I description BINDING SITE FOR RESIDUE CRS E 308 source : AC8 29) chain E residue 11 type sequence C description BINDING SITE FOR RESIDUE CRS E 308 source : AC8 30) chain F residue 7 type sequence C description BINDING SITE FOR RESIDUE CRS E 308 source : AC8 31) chain F residue 10 type sequence H description BINDING SITE FOR RESIDUE CRS E 308 source : AC8 32) chain F residue 11 type sequence L description BINDING SITE FOR RESIDUE CRS E 308 source : AC8 33) chain F residue 14 type sequence A description BINDING SITE FOR RESIDUE CRS E 308 source : AC8 34) chain J residue 5 type sequence H description BINDING SITE FOR RESIDUE CRS E 308 source : AC8 35) chain L residue 17 type sequence L description BINDING SITE FOR RESIDUE CRS E 308 source : AC8 36) chain B residue 17 type sequence L description BINDING SITE FOR RESIDUE CRS G 309 source : AC9 37) chain D residue 5 type sequence H description BINDING SITE FOR RESIDUE CRS G 309 source : AC9 38) chain G residue 6 type sequence C description BINDING SITE FOR RESIDUE CRS G 309 source : AC9 39) chain G residue 9 type sequence S description BINDING SITE FOR RESIDUE CRS G 309 source : AC9 40) chain G residue 10 type sequence I description BINDING SITE FOR RESIDUE CRS G 309 source : AC9 41) chain G residue 11 type sequence C description BINDING SITE FOR RESIDUE CRS G 309 source : AC9 42) chain H residue 11 type sequence L description BINDING SITE FOR RESIDUE CRS G 309 source : AC9 43) chain H residue 14 type sequence A description BINDING SITE FOR RESIDUE CRS G 309 source : AC9 44) chain B residue 5 type sequence H description BINDING SITE FOR RESIDUE CRS I 310 source : BC1 45) chain I residue 6 type sequence C description BINDING SITE FOR RESIDUE CRS I 310 source : BC1 46) chain I residue 10 type sequence I description BINDING SITE FOR RESIDUE CRS I 310 source : BC1 47) chain I residue 11 type sequence C description BINDING SITE FOR RESIDUE CRS I 310 source : BC1 48) chain J residue 11 type sequence L description BINDING SITE FOR RESIDUE CRS I 310 source : BC1 49) chain J residue 14 type sequence A description BINDING SITE FOR RESIDUE CRS I 310 source : BC1 50) chain F residue 17 type sequence L description BINDING SITE FOR RESIDUE CRS K 311 source : BC2 51) chain H residue 5 type sequence H description BINDING SITE FOR RESIDUE CRS K 311 source : BC2 52) chain K residue 6 type sequence C description BINDING SITE FOR RESIDUE CRS K 311 source : BC2 53) chain K residue 10 type sequence I description BINDING SITE FOR RESIDUE CRS K 311 source : BC2 54) chain K residue 11 type sequence C description BINDING SITE FOR RESIDUE CRS K 311 source : BC2 55) chain L residue 11 type sequence L description BINDING SITE FOR RESIDUE CRS K 311 source : BC2 56) chain L residue 14 type sequence A description BINDING SITE FOR RESIDUE CRS K 311 source : BC2 57) chain A residue 13 type sequence L description BINDING SITE FOR RESIDUE CRS A 312 source : BC3 58) chain A residue 14 type sequence Y description BINDING SITE FOR RESIDUE CRS A 312 source : BC3 59) chain G residue 13 type sequence L description BINDING SITE FOR RESIDUE CRS A 312 source : BC3 60) chain G residue 14 type sequence Y description BINDING SITE FOR RESIDUE CRS A 312 source : BC3 61) chain A residue 6-20 type prosite sequence CCTSICSLYQLENYC description INSULIN Insulin family signature. CCTSiCSlyqLenyC source prosite : PS00262

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