eF-site ID 1ev3-ABCD
PDB Code 1ev3
Chain A, B, C, D

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Title Structure of the rhombohedral form of the M-cresol/insulin R6 hexamer
Classification HORMONE/GROWTH FACTOR
Compound INSULIN
Source (INS_HUMAN)
Sequence A:  GIVEQCCTSICSLYQLENYCN
B:  FVNQHLCGSHLVEALYLVCGERGFFYTP
C:  GIVEQCCTSICSLYQLENYCN
D:  FVNQHLCGSHLVEALYLVCGERGFFYTP
Description (1)  INSULIN


Functional site

1) chain B
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE ZN B 31
source : AC1

2) chain B
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE ZN B 31
source : AC1

3) chain B
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE ZN B 31
source : AC1

4) chain D
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE ZN D 31
source : AC2

5) chain D
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE ZN D 31
source : AC2

6) chain D
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE ZN D 31
source : AC2

7) chain B
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE CL B 32
source : AC3

8) chain B
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE CL B 32
source : AC3

9) chain B
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE CL B 32
source : AC3

10) chain D
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE CL D 32
source : AC4

11) chain D
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE CL D 32
source : AC4

12) chain D
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE CL D 32
source : AC4

13) chain A
residue 6
type
sequence C
description BINDING SITE FOR RESIDUE CRS A 22
source : AC5

14) chain A
residue 10
type
sequence I
description BINDING SITE FOR RESIDUE CRS A 22
source : AC5

15) chain A
residue 11
type
sequence C
description BINDING SITE FOR RESIDUE CRS A 22
source : AC5

16) chain A
residue 16
type
sequence L
description BINDING SITE FOR RESIDUE CRS A 22
source : AC5

17) chain B
residue 5
type
sequence H
description BINDING SITE FOR RESIDUE CRS A 22
source : AC5

18) chain B
residue 11
type
sequence L
description BINDING SITE FOR RESIDUE CRS A 22
source : AC5

19) chain B
residue 17
type
sequence L
description BINDING SITE FOR RESIDUE CRS C 22
source : AC6

20) chain C
residue 6
type
sequence C
description BINDING SITE FOR RESIDUE CRS C 22
source : AC6

21) chain C
residue 9
type
sequence S
description BINDING SITE FOR RESIDUE CRS C 22
source : AC6

22) chain C
residue 10
type
sequence I
description BINDING SITE FOR RESIDUE CRS C 22
source : AC6

23) chain C
residue 11
type
sequence C
description BINDING SITE FOR RESIDUE CRS C 22
source : AC6

24) chain D
residue 5
type
sequence H
description BINDING SITE FOR RESIDUE CRS C 22
source : AC6

25) chain D
residue 11
type
sequence L
description BINDING SITE FOR RESIDUE CRS C 22
source : AC6

26) chain D
residue 14
type
sequence A
description BINDING SITE FOR RESIDUE CRS C 22
source : AC6

27) chain B
residue 18
type
sequence V
description BINDING SITE FOR RESIDUE CRS C 23
source : AC7

28) chain C
residue 13
type
sequence L
description BINDING SITE FOR RESIDUE CRS C 23
source : AC7

29) chain D
residue 18
type
sequence V
description BINDING SITE FOR RESIDUE CRS C 23
source : AC7

30) chain A
residue 6-20
type prosite
sequence CCTSICSLYQLENYC
description INSULIN Insulin family signature. CCTSiCSlyqLenyC
source prosite : PS00262


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