eF-site ID 1eo3-A PDB Code 1eo3 Chain A click to enlarge Title INHIBITION OF ECORV ENDONUCLEASE BY DEOXYRIBO-3'-S-PHOSPHOROTHIOLATES: A HIGH RESOLUTION X-RAY CRYSTALLOGRAPHIC STUDY Classification hydrolase/DNA Compound DNA (5'-D(*CP*AP*AP*GP*AP*(TSP)P*AP*TP*CP*TP*T)-3') Source (1EO3) Sequence A:  SLRSDLINALYDENQKYDVCGIISAEGKIYPLGSDTKVLS TIFELFSRPIINKIAEKHGYIVEEPKQQNHYPDFTLYKPS EPNKKIAIDIKTTYTNKENEKIKFTLGGYTSFIRNNTKNI VYPFDQYIAHWIIGYVYTRVATKSSLKTYNILNEIPKPYK GVKVFLQDKWVIAGDLAGSGNTTNIGSIHAHYKDFVEGKG IFDSEDEFLDYWRNYERTSQLRNDKYNNISEYRNWIYRGR K Description Functional site 1) chain A residue 45 type sequence E description BINDING SITE FOR RESIDUE MG A 501 source : AC1 2) chain A residue 74 type sequence D description BINDING SITE FOR RESIDUE MG A 501 source : AC1 3) chain A residue 74 type sequence D description BINDING SITE FOR RESIDUE MG A 502 source : AC2 4) chain A residue 91 type sequence I description BINDING SITE FOR RESIDUE MG A 502 source : AC2 5) chain A residue 18 type sequence Y description BINDING SITE FOR RESIDUE ACY A 601 source : AC5 6) chain A residue 19 type sequence D description BINDING SITE FOR RESIDUE ACY A 601 source : AC5 7) chain A residue 20 type sequence V description BINDING SITE FOR RESIDUE ACY A 601 source : AC5 8) chain A residue 47 type sequence F description BINDING SITE FOR RESIDUE ACY A 601 source : AC5 9) chain A residue 163 type sequence Y description BINDING SITE FOR RESIDUE ACY A 601 source : AC5 10) chain A residue 166 type sequence V description BINDING SITE FOR RESIDUE ACY A 601 source : AC5 11) chain A residue 75 type ACT_SITE sequence F description source Swiss-Prot : SWS_FT_FI1 12) chain A residue 91 type ACT_SITE sequence I description source Swiss-Prot : SWS_FT_FI1 13) chain A residue 93 type ACT_SITE sequence T description source Swiss-Prot : SWS_FT_FI1 14) chain A residue 46 type BINDING sequence L description source Swiss-Prot : SWS_FT_FI2 15) chain A residue 75 type BINDING sequence F description source Swiss-Prot : SWS_FT_FI2 16) chain A residue 91 type BINDING sequence I description source Swiss-Prot : SWS_FT_FI2

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