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eF-site ID
|
1emh-ABC |
|
PDB Code
|
1emh |
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Chain
|
A, B, C |
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click to enlarge
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Title
|
CRYSTAL STRUCTURE OF HUMAN URACIL-DNA GLYCOSYLASE BOUND TO UNCLEAVED SUBSTRATE-CONTAINING DNA |
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Classification
|
hydrolase/DNA |
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Compound
|
DNA (5'-D(*TP*GP*TP*(P2U)P*AP*TP*CP*TP*T)-3') |
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Source
|
null (1EMH) |
|
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Sequence
|
A: |
MEFFGESWKKHLSGEFGKPYFIKLMGFVAEERKHYTVYPP
PHQVFTWTQMCDIKDVKVVILGQDPYHGPNQAHGLCFSVQ
RPVPPPPSLENIYKELSTDIEDFVHPGHGDLSGWAKQGVL
LLNAVLTVRAHQANSHKERGWEQFTDAVVSWLNQNSNGLV
FLLWGSYAQKKGSAIDRKRHHVLQTAHPSPLSVYRGFFGC
RHFSKTNELLQKSGKKPIDWKEL
|
| B: |
TGTXATCTT
|
| C: |
AAAGATAACA
|
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Description
|
|
Functional site
|
|
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1)
|
chain |
A |
| residue |
142 |
| type |
ACT_SITE |
| sequence |
L
|
| description |
Proton acceptor => ECO:0000255|HAMAP-Rule:MF_03166
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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2)
|
chain |
A |
| residue |
283 |
| type |
MOD_RES |
| sequence |
H
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
A |
| residue |
138-147 |
| type |
prosite |
| sequence |
KVVILGQDPY
|
| description |
U_DNA_GLYCOSYLASE Uracil-DNA glycosylase signature. KVVIlGQDPY
|
| source |
prosite : PS00130
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