|
|
eF-site ID
|
1ea8-A |
|
PDB Code
|
1ea8 |
|
Chain
|
A |
|
click to enlarge
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|
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Title
|
Apolipoprotein E3 22kD fragment LYS146GLU mutant |
|
Classification
|
LIPID BINDING PROTEIN |
|
Compound
|
APOLIPOPROTEIN E |
|
Source
|
(APE_HUMAN) |
|
|
Sequence
|
A: |
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRA
LMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQA
RLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR
KLRERLLRDADDLQKRLAVY
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
75 |
| type |
CARBOHYD |
| sequence |
K
|
| description |
N-linked (Glc) (glycation) lysine => ECO:0000269|PubMed:10452964
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
2)
|
chain |
A |
| residue |
125 |
| type |
MOD_RES |
| sequence |
M
|
| description |
Methionine sulfoxide => ECO:0000250|UniProtKB:P08226
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
A |
| residue |
129 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by FAM20C => ECO:0000269|PubMed:26091039, ECO:0007744|PubMed:24275569
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
A |
| residue |
144 |
| type |
BINDING |
| sequence |
L
|
| description |
BINDING => ECO:0000269|PubMed:3947350
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|