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eF-site ID
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1e55-B |
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PDB Code
|
1e55 |
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Chain
|
B |
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click to enlarge
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Title
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Crystal structure of the inactive mutant Monocot (Maize ZMGlu1) beta-glucosidase ZMGluE191D in complex with the competitive inhibitor dhurrin |
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Classification
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HYDROLASE |
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Compound
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BETA-GLUCOSIDASE |
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Source
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(BGLC_MAIZE) |
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Sequence
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B: |
MLSPSEIPQRDWFPSDFTFGAATSAYQIEGAWNEDGKGES
NWDHFCHNHPERILDGSNSDIGANSYHMYKTDVRLLKEMG
MDAYRFSISWPRILPKGTKEGGINPDGIKYYRNLINLLLE
NGIEPYVTIFHWDVPQALEEKYGGFLDKSHKSIVEDYTYF
AKVCFDNFGDKVKNWLTFNDPQTFTSFSYGTGVFAPGRCS
PGLDCAYPTGNSLVEPYTAGHNILLAHAEAVDLYNKHYKR
DDTRIGLAFDVMGRVPYGTSFLDKQAEERSWDINLGWFLE
PVVRGDYPFSMRSLARERLPFFKDEQKEKLAGSYNMLGLN
YYTSRFSKNIDISPNYSPVLNTDDAYASQEVNGPDGKPIG
PPMGNPWIYMYPEGLKDLLMIMKNKYGNPPIYITENGIGD
VDTKETPLPMEAALNDYKRLDYIQRHIATLKESIDLGSNV
QGYFAWSLLDNFEWFAGFTERYGIVYVDRNNNCTRYMKES
AKWLKEFNTA
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Description
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Functional site
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|
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1)
|
chain |
B |
| residue |
457 |
| type |
BINDING |
| sequence |
W
|
| description |
BINDING => ECO:0000305|PubMed:11106394, ECO:0000305|PubMed:12684498, ECO:0007744|PDB:1E55, ECO:0007744|PDB:1E56, ECO:0007744|PDB:1H49
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| source |
Swiss-Prot : SWS_FT_FI6
|
|
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2)
|
chain |
B |
| residue |
464 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000305|PubMed:11106394, ECO:0000305|PubMed:12684498, ECO:0007744|PDB:1E55, ECO:0007744|PDB:1E56, ECO:0007744|PDB:1H49
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
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3)
|
chain |
B |
| residue |
191 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
Proton donor => ECO:0000250|UniProtKB:Q7XKV4
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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4)
|
chain |
B |
| residue |
406 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
Nucleophile => ECO:0000250|UniProtKB:Q7XKV4
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
B |
| residue |
38 |
| type |
BINDING |
| sequence |
Q
|
| description |
BINDING => ECO:0000305|PubMed:11106394, ECO:0000305|PubMed:12684498, ECO:0007744|PDB:1E56, ECO:0007744|PDB:1H49
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
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6)
|
chain |
B |
| residue |
142 |
| type |
BINDING |
| sequence |
H
|
| description |
BINDING => ECO:0000305|PubMed:11106394, ECO:0007744|PDB:1E56
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
7)
|
chain |
B |
| residue |
190 |
| type |
BINDING |
| sequence |
N
|
| description |
BINDING => ECO:0000305|PubMed:11106394, ECO:0007744|PDB:1E56
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
8)
|
chain |
B |
| residue |
333 |
| type |
BINDING |
| sequence |
Y
|
| description |
BINDING => ECO:0000305|PubMed:11106394, ECO:0007744|PDB:1E56
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
9)
|
chain |
B |
| residue |
473 |
| type |
BINDING |
| sequence |
Y
|
| description |
BINDING => ECO:0000305|PubMed:11106394, ECO:0007744|PDB:1E56
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
10)
|
chain |
B |
| residue |
406 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000250|UniProtKB:Q9SPP9
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
|