eF-site ID 1e4d-ABCD PDB Code 1e4d Chain A, B, C, D click to enlarge Title Structure of OXA10 beta-lactamase at pH 8.3 Classification BETA-LACTAMASE Compound BETA-LACTAMASE OXA-10 Source Pseudomonas aeruginosa (BLP2_PSEAE) Sequence A:  ITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARASK EYLPASTFXIPNAIIGLETGVIKNEHQVFKWDGKPRAMKQ WERDLTLRGAIQVSAVPVFQQIAREVGEVRMQKYLKKFSY GNQNISGGIDKFWLEGQLRISAVNQVEFLESLYLNKLSAS KENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVAW WVGWVEKETEVYFFAFNMDIDNESKLPLRKSIPTKIMESE GII B:  SITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARAS KEYLPASTFXIPNAIIGLETGVIKNEHQVFKWDGKPRAMK QWERDLTLRGAIQVSAVPVFQQIAREVGEVRMQKYLKKFS YGNQNISGGIDKFWLEGQLRISAVNQVEFLESLYLNKLSA SKENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVA WWVGWVEKETEVYFFAFNMDIDNESKLPLRKSIPTKIMES EGII C:  SITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARAS KEYLPASTFXIPNAIIGLETGVIKNEHQVFKWDGKPRAMK QWERDLTLRGAIQVSAVPVFQQIAREVGEVRMQKYLKKFS YGNQNISGGIDKFWLEGQLRISAVNQVEFLESLYLNKLSA SKENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVA WWVGWVEKETEVYFFAFNMDIDNESKLPLRKSIPTKIMES EGIIGG D:  SITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARAS KEYLPASTFXIPNAIIGLETGVIKNEHQVFKWDGKPRAMK QWERDLTLRGAIQVSAVPVFQQIAREVGEVRMQKYLKKFS YGNQNISGGIDKFWLEGQLRISAVNQVEFLESLYLNKLSA SKENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVA WWVGWVEKETEVYFFAFNMDIDNESKLPLRKSIPTKIMES EGIIGG Description Functional site 1) chain A residue 67 type sequence S description BINDING SITE FOR RESIDUE SO4 A 901 source : AC1 2) chain A residue 115 type sequence S description BINDING SITE FOR RESIDUE SO4 A 901 source : AC1 3) chain A residue 205 type sequence K description BINDING SITE FOR RESIDUE SO4 A 901 source : AC1 4) chain A residue 206 type sequence T description BINDING SITE FOR RESIDUE SO4 A 901 source : AC1 5) chain A residue 207 type sequence G description BINDING SITE FOR RESIDUE SO4 A 901 source : AC1 6) chain A residue 208 type sequence F description BINDING SITE FOR RESIDUE SO4 A 901 source : AC1 7) chain A residue 250 type sequence R description BINDING SITE FOR RESIDUE SO4 A 901 source : AC1 8) chain A residue 80 type sequence T description BINDING SITE FOR RESIDUE SO4 A 902 source : AC2 9) chain A residue 131 type sequence R description BINDING SITE FOR RESIDUE SO4 A 902 source : AC2 10) chain A residue 134 type sequence K description BINDING SITE FOR RESIDUE SO4 A 902 source : AC2 11) chain A residue 135 type sequence Y description BINDING SITE FOR RESIDUE SO4 A 902 source : AC2 12) chain A residue 99 type sequence M description BINDING SITE FOR RESIDUE SO4 A 903 source : AC3 13) chain A residue 100 type sequence K description BINDING SITE FOR RESIDUE SO4 A 903 source : AC3 14) chain A residue 101 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 903 source : AC3 15) chain A residue 128 type sequence G description BINDING SITE FOR RESIDUE SO4 A 904 source : AC4 16) chain A residue 129 type sequence E description BINDING SITE FOR RESIDUE SO4 A 904 source : AC4 17) chain A residue 130 type sequence V description BINDING SITE FOR RESIDUE SO4 A 904 source : AC4 18) chain B residue 85 type sequence N description BINDING SITE FOR RESIDUE SO4 B 901 source : AC5 19) chain D residue 176 type sequence N description BINDING SITE FOR RESIDUE SO4 B 901 source : AC5 20) chain D residue 182 type sequence K description BINDING SITE FOR RESIDUE SO4 B 901 source : AC5 21) chain B residue 198 type sequence P description BINDING SITE FOR RESIDUE SO4 B 902 source : AC6 22) chain B residue 199 type sequence E description BINDING SITE FOR RESIDUE SO4 B 902 source : AC6 23) chain B residue 227 type sequence E description BINDING SITE FOR RESIDUE SO4 B 902 source : AC6 24) chain B residue 229 type sequence E description BINDING SITE FOR RESIDUE SO4 B 902 source : AC6 25) chain D residue 107 type sequence T description BINDING SITE FOR RESIDUE SO4 B 902 source : AC6 26) chain D residue 109 type sequence R description BINDING SITE FOR RESIDUE SO4 B 902 source : AC6 27) chain B residue 67 type sequence S description BINDING SITE FOR RESIDUE SO4 B 903 source : AC7 28) chain B residue 115 type sequence S description BINDING SITE FOR RESIDUE SO4 B 903 source : AC7 29) chain B residue 205 type sequence K description BINDING SITE FOR RESIDUE SO4 B 903 source : AC7 30) chain B residue 206 type sequence T description BINDING SITE FOR RESIDUE SO4 B 903 source : AC7 31) chain B residue 207 type sequence G description BINDING SITE FOR RESIDUE SO4 B 903 source : AC7 32) chain B residue 208 type sequence F description BINDING SITE FOR RESIDUE SO4 B 903 source : AC7 33) chain B residue 250 type sequence R description BINDING SITE FOR RESIDUE SO4 B 903 source : AC7 34) chain B residue 160 type sequence R description BINDING SITE FOR RESIDUE SO4 B 904 source : AC8 35) chain B residue 80 type sequence T description BINDING SITE FOR RESIDUE SO4 B 905 source : AC9 36) chain B residue 131 type sequence R description BINDING SITE FOR RESIDUE SO4 B 905 source : AC9 37) chain B residue 134 type sequence K description BINDING SITE FOR RESIDUE SO4 B 905 source : AC9 38) chain B residue 135 type sequence Y description BINDING SITE FOR RESIDUE SO4 B 905 source : AC9 39) chain C residue 195 type sequence E description BINDING SITE FOR RESIDUE SO4 C 901 source : BC1 40) chain C residue 200 type sequence Y description BINDING SITE FOR RESIDUE SO4 C 901 source : BC1 41) chain C residue 202 type sequence V description BINDING SITE FOR RESIDUE SO4 C 901 source : BC1 42) chain C residue 222 type sequence W description BINDING SITE FOR RESIDUE SO4 C 901 source : BC1 43) chain C residue 226 type sequence V description BINDING SITE FOR RESIDUE SO4 C 901 source : BC1 44) chain C residue 255 type sequence T description BINDING SITE FOR RESIDUE SO4 C 901 source : BC1 45) chain C residue 258 type sequence M description BINDING SITE FOR RESIDUE SO4 C 901 source : BC1 46) chain C residue 206 type sequence T description BINDING SITE FOR RESIDUE SO4 C 902 source : BC2 47) chain C residue 247 type sequence L description BINDING SITE FOR RESIDUE SO4 C 902 source : BC2 48) chain C residue 248 type sequence P description BINDING SITE FOR RESIDUE SO4 C 902 source : BC2 49) chain C residue 250 type sequence R description BINDING SITE FOR RESIDUE SO4 C 902 source : BC2 50) chain C residue 251 type sequence K description BINDING SITE FOR RESIDUE SO4 C 902 source : BC2 51) chain C residue 99 type sequence M description BINDING SITE FOR RESIDUE SO4 C 903 source : BC3 52) chain C residue 100 type sequence K description BINDING SITE FOR RESIDUE SO4 C 903 source : BC3 53) chain C residue 101 type sequence Q description BINDING SITE FOR RESIDUE SO4 C 903 source : BC3 54) chain C residue 67 type sequence S description BINDING SITE FOR RESIDUE SO4 C 904 source : BC4 55) chain C residue 115 type sequence S description BINDING SITE FOR RESIDUE SO4 C 904 source : BC4 56) chain C residue 205 type sequence K description BINDING SITE FOR RESIDUE SO4 C 904 source : BC4 57) chain C residue 206 type sequence T description BINDING SITE FOR RESIDUE SO4 C 904 source : BC4 58) chain C residue 207 type sequence G description BINDING SITE FOR RESIDUE SO4 C 904 source : BC4 59) chain C residue 208 type sequence F description BINDING SITE FOR RESIDUE SO4 C 904 source : BC4 60) chain C residue 250 type sequence R description BINDING SITE FOR RESIDUE SO4 C 904 source : BC4 61) chain A residue 95 type sequence K description BINDING SITE FOR RESIDUE SO4 D 901 source : BC5 62) chain D residue 67 type sequence S description BINDING SITE FOR RESIDUE SO4 D 901 source : BC5 63) chain D residue 115 type sequence S description BINDING SITE FOR RESIDUE SO4 D 901 source : BC5 64) chain D residue 205 type sequence K description BINDING SITE FOR RESIDUE SO4 D 901 source : BC5 65) chain D residue 206 type sequence T description BINDING SITE FOR RESIDUE SO4 D 901 source : BC5 66) chain D residue 207 type sequence G description BINDING SITE FOR RESIDUE SO4 D 901 source : BC5 67) chain D residue 208 type sequence F description BINDING SITE FOR RESIDUE SO4 D 901 source : BC5 68) chain D residue 250 type sequence R description BINDING SITE FOR RESIDUE SO4 D 901 source : BC5 69) chain D residue 206 type sequence T description BINDING SITE FOR RESIDUE SO4 D 902 source : BC6 70) chain D residue 247 type sequence L description BINDING SITE FOR RESIDUE SO4 D 902 source : BC6 71) chain D residue 248 type sequence P description BINDING SITE FOR RESIDUE SO4 D 902 source : BC6 72) chain D residue 250 type sequence R description BINDING SITE FOR RESIDUE SO4 D 902 source : BC6 73) chain D residue 251 type sequence K description BINDING SITE FOR RESIDUE SO4 D 902 source : BC6 74) chain B residue 183 type sequence E description BINDING SITE FOR RESIDUE SO4 D 903 source : BC7 75) chain D residue 181 type sequence S description BINDING SITE FOR RESIDUE SO4 D 903 source : BC7 76) chain D residue 182 type sequence K description BINDING SITE FOR RESIDUE SO4 D 903 source : BC7 77) chain A residue 195 type sequence E description BINDING SITE FOR RESIDUE EDO A 911 source : BC8 78) chain A residue 200 type sequence Y description BINDING SITE FOR RESIDUE EDO A 911 source : BC8 79) chain A residue 202 type sequence V description BINDING SITE FOR RESIDUE EDO A 911 source : BC8 80) chain A residue 258 type sequence M description BINDING SITE FOR RESIDUE EDO A 911 source : BC8 81) chain A residue 259 type sequence E description BINDING SITE FOR RESIDUE EDO A 911 source : BC8 82) chain A residue 263 type sequence I description BINDING SITE FOR RESIDUE EDO A 911 source : BC8 83) chain B residue 195 type sequence E description BINDING SITE FOR RESIDUE EDO B 911 source : BC9 84) chain B residue 200 type sequence Y description BINDING SITE FOR RESIDUE EDO B 911 source : BC9 85) chain B residue 259 type sequence E description BINDING SITE FOR RESIDUE EDO B 911 source : BC9 86) chain B residue 263 type sequence I description BINDING SITE FOR RESIDUE EDO B 911 source : BC9 87) chain B residue 38 type sequence N description BINDING SITE FOR RESIDUE EDO B 912 source : CC1 88) chain B residue 217 type sequence P description BINDING SITE FOR RESIDUE EDO B 912 source : CC1 89) chain B residue 240 type sequence D description BINDING SITE FOR RESIDUE EDO B 912 source : CC1 90) chain A residue 107 type sequence T description BINDING SITE FOR RESIDUE EDO C 911 source : CC2 91) chain A residue 109 type sequence R description BINDING SITE FOR RESIDUE EDO C 911 source : CC2 92) chain C residue 198 type sequence P description BINDING SITE FOR RESIDUE EDO C 911 source : CC2 93) chain C residue 199 type sequence E description BINDING SITE FOR RESIDUE EDO C 911 source : CC2 94) chain C residue 200 type sequence Y description BINDING SITE FOR RESIDUE EDO C 911 source : CC2 95) chain C residue 229 type sequence E description BINDING SITE FOR RESIDUE EDO C 911 source : CC2 96) chain D residue 113 type sequence Q description BINDING SITE FOR RESIDUE EDO D 911 source : CC3 97) chain D residue 204 type sequence S description BINDING SITE FOR RESIDUE EDO D 911 source : CC3 98) chain D residue 205 type sequence K description BINDING SITE FOR RESIDUE EDO D 911 source : CC3 99) chain D residue 206 type sequence T description BINDING SITE FOR RESIDUE EDO D 911 source : CC3 100) chain D residue 195 type sequence E description BINDING SITE FOR RESIDUE EDO D 912 source : CC4 101) chain D residue 255 type sequence T description BINDING SITE FOR RESIDUE EDO D 912 source : CC4 102) chain A residue 65-75 type prosite sequence PASTFXIPNAI description BETA_LACTAMASE_D Beta-lactamase class-D active site. PaSTFKIPnAI source prosite : PS00337 103) chain A residue 67 type ACT_SITE sequence S description Acyl-ester intermediate source Swiss-Prot : SWS_FT_FI1 104) chain B residue 67 type ACT_SITE sequence S description Acyl-ester intermediate source Swiss-Prot : SWS_FT_FI1 105) chain C residue 67 type ACT_SITE sequence S description Acyl-ester intermediate source Swiss-Prot : SWS_FT_FI1 106) chain D residue 67 type ACT_SITE sequence S description Acyl-ester intermediate source Swiss-Prot : SWS_FT_FI1 107) chain A residue 205 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 108) chain B residue 205 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 109) chain C residue 205 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 110) chain D residue 205 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 111) chain A residue 70 type MOD_RES sequence X description N6-carboxylysine => ECO:0000269|PubMed:11188693 source Swiss-Prot : SWS_FT_FI3 112) chain B residue 70 type MOD_RES sequence X description N6-carboxylysine => ECO:0000269|PubMed:11188693 source Swiss-Prot : SWS_FT_FI3 113) chain C residue 70 type MOD_RES sequence X description N6-carboxylysine => ECO:0000269|PubMed:11188693 source Swiss-Prot : SWS_FT_FI3 114) chain D residue 70 type MOD_RES sequence X description N6-carboxylysine => ECO:0000269|PubMed:11188693 source Swiss-Prot : SWS_FT_FI3

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