eF-site ID 1e3u-ABCD PDB Code 1e3u Chain A, B, C, D click to enlarge Title MAD structure of OXA10 class D beta-lactamase Classification BETA-LACTAMASE Compound BETA-LACTAMASE OXA-10 Source (BLP2_PSEAE) Sequence A:  ITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARASK EYLPASTFKIPNAIIGLETGVIKNEHQVFKWDGKPRAMKQ WERDLTLRGAIQVSAVPVFQQIAREVGEVRMQKYLKKFSY GNQNISGGIDKFWLEGQLRISAVNQVEFLESLYLNKLSAS KENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVAW WVGWVEKETEVYFFAFNMDIDNESKLPLRKSIPTKIMESE GII B:  ITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARASK EYLPASTFKIPNAIIGLETGVIKNEHQVFKWDGKPRAMKQ WERDLTLRGAIQVSAVPVFQQIAREVGEVRMQKYLKKFSY GNQNISGGIDKFWLEGQLRISAVNQVEFLESLYLNKLSAS KENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVAW WVGWVEKETEVYFFAFNMDIDNESKLPLRKSIPTKIMESE GII C:  ITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARASK EYLPASTFKIPNAIIGLETGVIKNEHQVFKWDRAMKQWER DLTLRGAIQVSAVPVFQQIAREVGEVRMQKYLKKFSYGNQ NISGGIDKFWLEGQLRISAVNQVEFLESLYLNKLSASKEN QLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVAWWVG WVEKETEVYFFAFNMDIDNESKLPLRKSIPTKIMESEGII GG D:  ITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARASK EYLPASTFKIPNAIIGLETGVIKNEHQVFKWPRAMKQWER DLTLRGAIQVSAVPVFQQIAREVGEVRMQKYLKKFSYGNQ NISGGIDKFWLEGQLRISAVNQVEFLESLYLNKLSASKEN QLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVAWWVG WVEKETEVYFFAFNMDIDNESKLPLRKSIPTKIMESEGII GG Description (1)  BETA-LACTAMASE OXA-10 (E.C.3.5.2.6) Functional site 1) chain A residue 66 type sequence A description BINDING SITE FOR RESIDUE AUC E 1 source : AC1 2) chain A residue 67 type sequence S description BINDING SITE FOR RESIDUE AUC E 1 source : AC1 3) chain A residue 69 type sequence F description BINDING SITE FOR RESIDUE AUC E 1 source : AC1 4) chain A residue 70 type sequence K description BINDING SITE FOR RESIDUE AUC E 1 source : AC1 5) chain A residue 73 type sequence N description BINDING SITE FOR RESIDUE AUC E 1 source : AC1 6) chain A residue 120 type sequence F description BINDING SITE FOR RESIDUE AUC E 1 source : AC1 7) chain A residue 154 type sequence W description BINDING SITE FOR RESIDUE AUC E 1 source : AC1 8) chain B residue 66 type sequence A description BINDING SITE FOR RESIDUE AUC E 2 source : AC2 9) chain B residue 67 type sequence S description BINDING SITE FOR RESIDUE AUC E 2 source : AC2 10) chain B residue 69 type sequence F description BINDING SITE FOR RESIDUE AUC E 2 source : AC2 11) chain B residue 70 type sequence K description BINDING SITE FOR RESIDUE AUC E 2 source : AC2 12) chain B residue 73 type sequence N description BINDING SITE FOR RESIDUE AUC E 2 source : AC2 13) chain B residue 120 type sequence F description BINDING SITE FOR RESIDUE AUC E 2 source : AC2 14) chain B residue 154 type sequence W description BINDING SITE FOR RESIDUE AUC E 2 source : AC2 15) chain C residue 70 type sequence K description BINDING SITE FOR RESIDUE AUC E 3 source : AC3 16) chain C residue 116 type sequence A description BINDING SITE FOR RESIDUE AUC E 3 source : AC3 17) chain C residue 117 type sequence V description BINDING SITE FOR RESIDUE AUC E 3 source : AC3 18) chain C residue 154 type sequence W description BINDING SITE FOR RESIDUE AUC E 3 source : AC3 19) chain B residue 95 type sequence K description BINDING SITE FOR RESIDUE AUC E 4 source : AC4 20) chain C residue 66 type sequence A description BINDING SITE FOR RESIDUE AUC E 4 source : AC4 21) chain C residue 67 type sequence S description BINDING SITE FOR RESIDUE AUC E 4 source : AC4 22) chain C residue 70 type sequence K description BINDING SITE FOR RESIDUE AUC E 4 source : AC4 23) chain C residue 73 type sequence N description BINDING SITE FOR RESIDUE AUC E 4 source : AC4 24) chain C residue 120 type sequence F description BINDING SITE FOR RESIDUE AUC E 4 source : AC4 25) chain C residue 154 type sequence W description BINDING SITE FOR RESIDUE AUC E 4 source : AC4 26) chain C residue 133 type sequence Q description BINDING SITE FOR RESIDUE AUC E 5 source : AC5 27) chain D residue 66 type sequence A description BINDING SITE FOR RESIDUE AUC E 6 source : AC6 28) chain D residue 67 type sequence S description BINDING SITE FOR RESIDUE AUC E 6 source : AC6 29) chain D residue 70 type sequence K description BINDING SITE FOR RESIDUE AUC E 6 source : AC6 30) chain D residue 73 type sequence N description BINDING SITE FOR RESIDUE AUC E 6 source : AC6 31) chain D residue 120 type sequence F description BINDING SITE FOR RESIDUE AUC E 6 source : AC6 32) chain D residue 154 type sequence W description BINDING SITE FOR RESIDUE AUC E 6 source : AC6 33) chain D residue 70 type sequence K description BINDING SITE FOR RESIDUE AUC E 7 source : AC7 34) chain D residue 116 type sequence A description BINDING SITE FOR RESIDUE AUC E 7 source : AC7 35) chain D residue 117 type sequence V description BINDING SITE FOR RESIDUE AUC E 7 source : AC7 36) chain D residue 154 type sequence W description BINDING SITE FOR RESIDUE AUC E 7 source : AC7 37) chain D residue 133 type sequence Q description BINDING SITE FOR RESIDUE AUC E 8 source : AC8 38) chain A residue 115 type sequence S description BINDING SITE FOR RESIDUE SO4 E 9 source : AC9 39) chain A residue 206 type sequence T description BINDING SITE FOR RESIDUE SO4 E 9 source : AC9 40) chain A residue 207 type sequence G description BINDING SITE FOR RESIDUE SO4 E 9 source : AC9 41) chain A residue 208 type sequence F description BINDING SITE FOR RESIDUE SO4 E 9 source : AC9 42) chain A residue 250 type sequence R description BINDING SITE FOR RESIDUE SO4 E 9 source : AC9 43) chain A residue 131 type sequence R description BINDING SITE FOR RESIDUE SO4 E 10 source : BC1 44) chain A residue 134 type sequence K description BINDING SITE FOR RESIDUE SO4 E 10 source : BC1 45) chain A residue 135 type sequence Y description BINDING SITE FOR RESIDUE SO4 E 10 source : BC1 46) chain A residue 160 type sequence R description BINDING SITE FOR RESIDUE SO4 E 11 source : BC2 47) chain A residue 22 type sequence I description BINDING SITE FOR RESIDUE SO4 E 12 source : BC3 48) chain C residue 33 type sequence S description BINDING SITE FOR RESIDUE SO4 E 12 source : BC3 49) chain C residue 36 type sequence A description BINDING SITE FOR RESIDUE SO4 E 12 source : BC3 50) chain C residue 37 type sequence V description BINDING SITE FOR RESIDUE SO4 E 12 source : BC3 51) chain C residue 38 type sequence N description BINDING SITE FOR RESIDUE SO4 E 12 source : BC3 52) chain B residue 115 type sequence S description BINDING SITE FOR RESIDUE SO4 E 13 source : BC4 53) chain B residue 205 type sequence K description BINDING SITE FOR RESIDUE SO4 E 13 source : BC4 54) chain B residue 206 type sequence T description BINDING SITE FOR RESIDUE SO4 E 13 source : BC4 55) chain B residue 207 type sequence G description BINDING SITE FOR RESIDUE SO4 E 13 source : BC4 56) chain B residue 208 type sequence F description BINDING SITE FOR RESIDUE SO4 E 13 source : BC4 57) chain B residue 250 type sequence R description BINDING SITE FOR RESIDUE SO4 E 13 source : BC4 58) chain B residue 99 type sequence M description BINDING SITE FOR RESIDUE SO4 E 14 source : BC5 59) chain B residue 100 type sequence K description BINDING SITE FOR RESIDUE SO4 E 14 source : BC5 60) chain B residue 101 type sequence Q description BINDING SITE FOR RESIDUE SO4 E 14 source : BC5 61) chain B residue 35 type sequence E description BINDING SITE FOR RESIDUE SO4 E 15 source : BC6 62) chain B residue 245 type sequence S description BINDING SITE FOR RESIDUE SO4 E 15 source : BC6 63) chain B residue 246 type sequence K description BINDING SITE FOR RESIDUE SO4 E 15 source : BC6 64) chain B residue 198 type sequence P description BINDING SITE FOR RESIDUE SO4 E 16 source : BC7 65) chain B residue 199 type sequence E description BINDING SITE FOR RESIDUE SO4 E 16 source : BC7 66) chain B residue 201 type sequence L description BINDING SITE FOR RESIDUE SO4 E 16 source : BC7 67) chain B residue 227 type sequence E description BINDING SITE FOR RESIDUE SO4 E 16 source : BC7 68) chain B residue 229 type sequence E description BINDING SITE FOR RESIDUE SO4 E 16 source : BC7 69) chain D residue 107 type sequence T description BINDING SITE FOR RESIDUE SO4 E 16 source : BC7 70) chain D residue 109 type sequence R description BINDING SITE FOR RESIDUE SO4 E 16 source : BC7 71) chain B residue 95 type sequence K description BINDING SITE FOR RESIDUE SO4 E 17 source : BC8 72) chain C residue 67 type sequence S description BINDING SITE FOR RESIDUE SO4 E 17 source : BC8 73) chain C residue 206 type sequence T description BINDING SITE FOR RESIDUE SO4 E 17 source : BC8 74) chain C residue 207 type sequence G description BINDING SITE FOR RESIDUE SO4 E 17 source : BC8 75) chain C residue 208 type sequence F description BINDING SITE FOR RESIDUE SO4 E 17 source : BC8 76) chain C residue 250 type sequence R description BINDING SITE FOR RESIDUE SO4 E 17 source : BC8 77) chain C residue 181 type sequence S description BINDING SITE FOR RESIDUE SO4 E 18 source : BC9 78) chain C residue 182 type sequence K description BINDING SITE FOR RESIDUE SO4 E 18 source : BC9 79) chain A residue 95 type sequence K description BINDING SITE FOR RESIDUE SO4 E 19 source : CC1 80) chain D residue 67 type sequence S description BINDING SITE FOR RESIDUE SO4 E 19 source : CC1 81) chain D residue 206 type sequence T description BINDING SITE FOR RESIDUE SO4 E 19 source : CC1 82) chain D residue 207 type sequence G description BINDING SITE FOR RESIDUE SO4 E 19 source : CC1 83) chain D residue 208 type sequence F description BINDING SITE FOR RESIDUE SO4 E 19 source : CC1 84) chain D residue 250 type sequence R description BINDING SITE FOR RESIDUE SO4 E 19 source : CC1 85) chain B residue 183 type sequence E description BINDING SITE FOR RESIDUE SO4 E 20 source : CC2 86) chain D residue 181 type sequence S description BINDING SITE FOR RESIDUE SO4 E 20 source : CC2 87) chain D residue 182 type sequence K description BINDING SITE FOR RESIDUE SO4 E 20 source : CC2 88) chain D residue 213 type sequence T description BINDING SITE FOR RESIDUE SO4 E 21 source : CC3 89) chain D residue 215 type sequence S description BINDING SITE FOR RESIDUE SO4 E 21 source : CC3 90) chain D residue 216 type sequence N description BINDING SITE FOR RESIDUE SO4 E 21 source : CC3 91) chain A residue 128 type sequence G description BINDING SITE FOR RESIDUE SO4 E 22 source : CC4 92) chain A residue 129 type sequence E description BINDING SITE FOR RESIDUE SO4 E 22 source : CC4 93) chain A residue 130 type sequence V description BINDING SITE FOR RESIDUE SO4 E 22 source : CC4 94) chain A residue 107 type sequence T description BINDING SITE FOR RESIDUE SO4 E 23 source : CC5 95) chain A residue 109 type sequence R description BINDING SITE FOR RESIDUE SO4 E 23 source : CC5 96) chain C residue 198 type sequence P description BINDING SITE FOR RESIDUE SO4 E 23 source : CC5 97) chain C residue 199 type sequence E description BINDING SITE FOR RESIDUE SO4 E 23 source : CC5 98) chain C residue 201 type sequence L description BINDING SITE FOR RESIDUE SO4 E 23 source : CC5 99) chain C residue 227 type sequence E description BINDING SITE FOR RESIDUE SO4 E 23 source : CC5 100) chain C residue 229 type sequence E description BINDING SITE FOR RESIDUE SO4 E 23 source : CC5 101) chain C residue 195 type sequence E description BINDING SITE FOR RESIDUE EDO E 24 source : CC6 102) chain C residue 200 type sequence Y description BINDING SITE FOR RESIDUE EDO E 24 source : CC6 103) chain C residue 29 type sequence N description BINDING SITE FOR RESIDUE EDO E 25 source : CC7 104) chain C residue 32 type sequence F description BINDING SITE FOR RESIDUE EDO E 25 source : CC7 105) chain C residue 37 type sequence V description BINDING SITE FOR RESIDUE EDO E 25 source : CC7 106) chain C residue 38 type sequence N description BINDING SITE FOR RESIDUE EDO E 25 source : CC7 107) chain C residue 39 type sequence G description BINDING SITE FOR RESIDUE EDO E 25 source : CC7 108) chain C residue 54 type sequence N description BINDING SITE FOR RESIDUE EDO E 25 source : CC7 109) chain B residue 29 type sequence N description BINDING SITE FOR RESIDUE EDO E 26 source : CC8 110) chain B residue 37 type sequence V description BINDING SITE FOR RESIDUE EDO E 26 source : CC8 111) chain B residue 38 type sequence N description BINDING SITE FOR RESIDUE EDO E 26 source : CC8 112) chain B residue 39 type sequence G description BINDING SITE FOR RESIDUE EDO E 26 source : CC8 113) chain B residue 54 type sequence N description BINDING SITE FOR RESIDUE EDO E 26 source : CC8 114) chain B residue 261 type sequence E description BINDING SITE FOR RESIDUE EDO E 27 source : CC9 115) chain B residue 107 type sequence T description BINDING SITE FOR RESIDUE EDO E 28 source : DC1 116) chain B residue 109 type sequence R description BINDING SITE FOR RESIDUE EDO E 28 source : DC1 117) chain D residue 198 type sequence P description BINDING SITE FOR RESIDUE EDO E 28 source : DC1 118) chain D residue 199 type sequence E description BINDING SITE FOR RESIDUE EDO E 28 source : DC1 119) chain D residue 229 type sequence E description BINDING SITE FOR RESIDUE EDO E 28 source : DC1 120) chain B residue 80 type sequence T description BINDING SITE FOR RESIDUE EDO E 29 source : DC2 121) chain B residue 131 type sequence R description BINDING SITE FOR RESIDUE EDO E 29 source : DC2 122) chain B residue 134 type sequence K description BINDING SITE FOR RESIDUE EDO E 29 source : DC2 123) chain B residue 135 type sequence Y description BINDING SITE FOR RESIDUE EDO E 29 source : DC2 124) chain A residue 199 type sequence E description BINDING SITE FOR RESIDUE EDO E 30 source : DC3 125) chain A residue 227 type sequence E description BINDING SITE FOR RESIDUE EDO E 30 source : DC3 126) chain A residue 229 type sequence E description BINDING SITE FOR RESIDUE EDO E 30 source : DC3 127) chain C residue 107 type sequence T description BINDING SITE FOR RESIDUE EDO E 30 source : DC3 128) chain C residue 146 type sequence I description BINDING SITE FOR RESIDUE EDO E 31 source : DC4 129) chain C residue 147 type sequence S description BINDING SITE FOR RESIDUE EDO E 31 source : DC4 130) chain C residue 148 type sequence G description BINDING SITE FOR RESIDUE EDO E 31 source : DC4 131) chain C residue 149 type sequence G description BINDING SITE FOR RESIDUE EDO E 31 source : DC4 132) chain C residue 150 type sequence I description BINDING SITE FOR RESIDUE EDO E 31 source : DC4 133) chain A residue 36 type sequence A description BINDING SITE FOR RESIDUE EDO E 32 source : DC5 134) chain A residue 217 type sequence P description BINDING SITE FOR RESIDUE EDO E 32 source : DC5 135) chain A residue 240 type sequence D description BINDING SITE FOR RESIDUE EDO E 32 source : DC5 136) chain A residue 242 type sequence D description BINDING SITE FOR RESIDUE EDO E 32 source : DC5 137) chain B residue 195 type sequence E description BINDING SITE FOR RESIDUE EDO E 33 source : DC6 138) chain B residue 200 type sequence Y description BINDING SITE FOR RESIDUE EDO E 33 source : DC6 139) chain B residue 202 type sequence V description BINDING SITE FOR RESIDUE EDO E 33 source : DC6 140) chain B residue 258 type sequence M description BINDING SITE FOR RESIDUE EDO E 33 source : DC6 141) chain B residue 259 type sequence E description BINDING SITE FOR RESIDUE EDO E 33 source : DC6 142) chain B residue 263 type sequence I description BINDING SITE FOR RESIDUE EDO E 33 source : DC6 143) chain B residue 217 type sequence P description BINDING SITE FOR RESIDUE EDO E 34 source : DC7 144) chain B residue 240 type sequence D description BINDING SITE FOR RESIDUE EDO E 34 source : DC7 145) chain B residue 143 type sequence N description BINDING SITE FOR RESIDUE EDO E 35 source : DC8 146) chain B residue 145 type sequence N description BINDING SITE FOR RESIDUE EDO E 35 source : DC8 147) chain A residue 65-75 type prosite sequence PASTFKIPNAI description BETA_LACTAMASE_D Beta-lactamase class-D active site. PaSTFKIPnAI source prosite : PS00337 148) chain D residue 65-75 type prosite sequence PASTFKIPNAI description BETA_LACTAMASE_D Beta-lactamase class-D active site. PaSTFKIPnAI source prosite : PS00337 149) chain D residue 67 type ACT_SITE sequence S description Acyl-ester intermediate source Swiss-Prot : SWS_FT_FI1 150) chain B residue 67 type ACT_SITE sequence S description Acyl-ester intermediate source Swiss-Prot : SWS_FT_FI1 151) chain C residue 67 type ACT_SITE sequence S description Acyl-ester intermediate source Swiss-Prot : SWS_FT_FI1 152) chain D residue 205 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 153) chain B residue 205 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 154) chain C residue 205 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 155) chain D residue 70 type MOD_RES sequence K description N6-carboxylysine => ECO:0000269|PubMed:11188693 source Swiss-Prot : SWS_FT_FI3 156) chain B residue 70 type MOD_RES sequence K description N6-carboxylysine => ECO:0000269|PubMed:11188693 source Swiss-Prot : SWS_FT_FI3 157) chain C residue 70 type MOD_RES sequence K description N6-carboxylysine => ECO:0000269|PubMed:11188693 source Swiss-Prot : SWS_FT_FI3

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