eF-site ID 1e25-A PDB Code 1e25 Chain A click to enlarge Title The high resolution structure of PER-1 class A beta-lactamase Classification HYDROLASE Compound EXTENDED-SPECTRUM BETA-LACTAMASE PER-1 Source Pseudomonas aeruginosa (BLE1_PSEAE) Sequence A:  SPLLKEQIESIVIGKKATVGVAVWGPDDLEPLLINPFEKF PMQSVFKLHLAMLVLHQVDQGKLDLNQTVIVNRAKVLQNT WAPIMKAYQGDEFSVPVQQLLQYSVSHSDNVACDLLFELV GGPAALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTS MKGAAEILKKFEQKTQLSETSQALLWKWMVETTTGPERLK GLLPAGTVVAHKTGTSQIKAGKTAATNDLGIILLPDGRPL LVAVFVKDSAESSRTNEAIIAQVAQTAYQFELKKLSAL Description Functional site 1) chain A residue 70 type sequence S description BINDING SITE FOR RESIDUE SO4 A 500 source : AC1 2) chain A residue 130 type sequence S description BINDING SITE FOR RESIDUE SO4 A 500 source : AC1 3) chain A residue 234 type sequence K description BINDING SITE FOR RESIDUE SO4 A 500 source : AC1 4) chain A residue 235 type sequence T description BINDING SITE FOR RESIDUE SO4 A 500 source : AC1 5) chain A residue 236 type sequence G description BINDING SITE FOR RESIDUE SO4 A 500 source : AC1 6) chain A residue 237 type sequence T description BINDING SITE FOR RESIDUE SO4 A 500 source : AC1 7) chain A residue 66-81 type prosite sequence FPMQSVFKLHLAMLVL description BETA_LACTAMASE_A Beta-lactamase class-A active site. FpMQSVfKlhlAMLVL source prosite : PS00146 8) chain A residue 70 type ACT_SITE sequence S description Acyl-ester intermediate => ECO:0000255|PROSITE-ProRule:PRU10101 source Swiss-Prot : SWS_FT_FI1 9) chain A residue 234 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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