|
|
eF-site ID
|
1e1h-C |
|
PDB Code
|
1e1h |
|
Chain
|
C |
|
click to enlarge
|
|
|
Title
|
Crystal Structure of recombinant Botulinum Neurotoxin Type A Light Chain, self-inhibiting Zn endopeptidase. |
|
Classification
|
HYDROLASE |
|
Compound
|
BOTULINUM NEUROTOXIN TYPE A LIGHT CHAIN |
|
Source
|
(1E1H) |
|
|
Sequence
|
C: |
MAYKDPVNGVDIAYIKIPNAGQMQPVKAFKIHNKIWVIPE
RDTFTNPEEGDLNPPPEAKQVPVSYYDSTYLSTDNEKDNY
LKGVTKLFERIYSTDLGRMLLTSIVRGIPFWGGSTIDTEL
KVIDTNCINVIQPDGSYRSEELNLVIIGPSADIIQFECKS
FGHDVLNLTRNGYGSTQYIRFSPDFTFGFEESLGAGKFAT
DPAVTLAHELIHAEHRLYGIAINPNRVFKVNTNAY
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
249 |
| type |
|
| sequence |
Y
|
| description |
BINDING SITE FOR RESIDUE ZN A 501
|
| source |
: AC1
|
|
|
2)
|
chain |
C |
| residue |
222 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN C 502
|
| source |
: AC2
|
|
|
3)
|
chain |
C |
| residue |
226 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN C 502
|
| source |
: AC2
|
|
|
4)
|
chain |
C |
| residue |
222 |
| type |
SITE |
| sequence |
H
|
| description |
Transition state stabilizer => ECO:0000305|PubMed:16846233
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
C |
| residue |
226 |
| type |
SITE |
| sequence |
H
|
| description |
Transition state stabilizer => ECO:0000305|PubMed:16846233
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|