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eF-site ID
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1dzg-IL |
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PDB Code
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1dzg |
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Chain
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I, L |
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click to enlarge
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Title
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N135Q-S380C-ANTITHROMBIN-III |
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Classification
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BLOOD CLOTTING |
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Compound
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ANTITHROMBIN-III |
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Source
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ORGANISM_COMMON: HUMAN; ORGANISM_SCIENTIFIC: HOMO SAPIENS; |
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Sequence
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I: |
PVDICTAKPRDIPMNPMCIYRSPEKKSEQKIPEATNRRVW
ELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAM
TKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCR
LYRKAQKSSKLVSANRLFGDKSLTFNETYQDISELVYGAK
LQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINE
LTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSA
SMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLILPKPE
KSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGF
SLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFH
KAFLEVNEEGCEAAASTAVVIAGRSLNPNRVTFKANRPFL
VFIREVPLNTIIFMGRVANPCV
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| L: |
ICTAKPRDIPMNPMCIYRSPEATNRRVWELSKANSRFATT
FYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQ
LMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLV
SANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQ
SRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYF
KGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYR
RVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTP
EVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLV
DLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSE
AAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTII
FMGRVANPC
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Description
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Functional site
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|
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1)
|
chain |
L |
| residue |
155 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19838169, ECO:0000269|Ref.10
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| source |
Swiss-Prot : SWS_FT_FI7
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2)
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chain |
L |
| residue |
192 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16263699, ECO:0000269|PubMed:16335952, ECO:0000269|Ref.10
|
| source |
Swiss-Prot : SWS_FT_FI8
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3)
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chain |
L |
| residue |
393 |
| type |
SITE |
| sequence |
R
|
| description |
Reactive bond => ECO:0000269|PubMed:7238875
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| source |
Swiss-Prot : SWS_FT_FI2
|
|
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4)
|
chain |
L |
| residue |
96 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218, ECO:0000269|Ref.10
|
| source |
Swiss-Prot : SWS_FT_FI5
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5)
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chain |
L |
| residue |
135 |
| type |
CARBOHYD |
| sequence |
N
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|Ref.10
|
| source |
Swiss-Prot : SWS_FT_FI6
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6)
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chain |
L |
| residue |
402-412 |
| type |
prosite |
| sequence |
FKANRPFLVFI
|
| description |
SERPIN Serpins signature. FKANRPFLVfI
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| source |
prosite : PS00284
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|
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7)
|
chain |
I |
| residue |
402-412 |
| type |
prosite |
| sequence |
FKANRPFLVFI
|
| description |
SERPIN Serpins signature. FKANRPFLVfI
|
| source |
prosite : PS00284
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|
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8)
|
chain |
L |
| residue |
49 |
| type |
BINDING |
| sequence |
W
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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9)
|
chain |
L |
| residue |
129 |
| type |
BINDING |
| sequence |
R
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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10)
|
chain |
L |
| residue |
145 |
| type |
BINDING |
| sequence |
R
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
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