eF-site ID 1dyt-B PDB Code 1dyt Chain B click to enlarge Title X-ray crystal structure of ECP (RNase 3) at 1.75 A Classification HYDROLASE Compound EOSINOPHIL CATIONIC PROTEIN Source null (ECP_HUMAN) Sequence B:  RPPQFTRAQWFAIQHISLNPPRCTIAMRAINNYRWRCKNQ NTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPL LHCDLINPGAQNISNCRYADRPGRRFYVVACDNRDPRDSP RYPVVPVHLDTTI Description (1)  EOSINOPHIL CATIONIC PROTEIN (E.C.3.1.27.-) Functional site 1) chain B residue 34 type sequence R description BINDING SITE FOR RESIDUE FE B 300 source : AC1 2) chain B residue 121 type sequence R description BINDING SITE FOR RESIDUE CIT A 301 source : AC3 3) chain B residue 46 type sequence T description BINDING SITE FOR RESIDUE CIT B 301 source : AC4 4) chain B residue 50 type sequence N description BINDING SITE FOR RESIDUE CIT B 301 source : AC4 5) chain B residue 54 type sequence V description BINDING SITE FOR RESIDUE CIT B 301 source : AC4 6) chain B residue 74 type sequence S description BINDING SITE FOR RESIDUE CIT B 301 source : AC4 7) chain B residue 75 type sequence R description BINDING SITE FOR RESIDUE CIT B 301 source : AC4 8) chain B residue 76 type sequence F description BINDING SITE FOR RESIDUE CIT B 301 source : AC4 9) chain B residue 78 type sequence V description BINDING SITE FOR RESIDUE CIT B 301 source : AC4 10) chain B residue 107 type sequence Y description BINDING SITE FOR RESIDUE CIT B 301 source : AC4 11) chain B residue 34 type sequence R description BINDING SITE FOR RESIDUE CIT B 302 source : AC6 12) chain B residue 36 type sequence R description BINDING SITE FOR RESIDUE CIT B 302 source : AC6 13) chain B residue 37 type sequence C description BINDING SITE FOR RESIDUE CIT B 302 source : AC6 14) chain B residue 38 type sequence K description BINDING SITE FOR RESIDUE CIT B 302 source : AC6 15) chain B residue 39 type sequence N description BINDING SITE FOR RESIDUE CIT B 302 source : AC6 16) chain B residue 40 type sequence Q description BINDING SITE FOR RESIDUE CIT B 302 source : AC6 17) chain B residue 35 type SITE sequence W description May be involved in LPS- and LTA-binding source Swiss-Prot : SWS_FT_FI5 18) chain B residue 33 type MOD_RES sequence Y description 3'-nitrotyrosine => ECO:0000269|PubMed:18694936 source Swiss-Prot : SWS_FT_FI6 19) chain B residue 15 type ACT_SITE sequence H description Proton acceptor source Swiss-Prot : SWS_FT_FI1 20) chain B residue 128 type ACT_SITE sequence H description Proton donor source Swiss-Prot : SWS_FT_FI2 21) chain B residue 38 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3 22) chain B residue 33 type SITE sequence Y description May be involved in LPS-binding source Swiss-Prot : SWS_FT_FI4 23) chain B residue 57 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI7 24) chain B residue 65 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI7 25) chain B residue 92 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI7

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