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|
eF-site ID
|
1dwo-B |
|
PDB Code
|
1dwo |
|
Chain
|
B |
|
click to enlarge
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Title
|
Crystal Structure of Hydroxynitrile Lyase from Manihot esculenta in Complex with Substrates Acetone and Chloroacetone:Implications for the Mechanism of Cyanogenesis |
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Classification
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HYDROXYNITRILE LYASE |
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Compound
|
HYDROXYNITRILE LYASE |
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Source
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(HNL_MANES) |
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Sequence
|
B: |
MVTAHFVLIHTICHGAWIWHKLKPALERAGHKVTALDMAA
SGIDPRQIEQINSFDEYSEPLLTFLEKLPQGEKVIIVGES
CAGLNIAIAADRYVDKIAAGVFHNSLLPDTVHSPSYTVEK
LLESFPDWRDTEYFTFTNITGETITTMKLGFVLLRENLFT
KCTDGEYELAKMVMRKGSLFQNVLAQRPKFTEKGYGSIKK
VYIWTDQDKIFLPDFQRWQIANYKPDKVYQVQGGDHKLQL
TKTEEVAHILQEVADAYA
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Description
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Functional site
|
|
|
1)
|
chain |
B |
| residue |
81 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Proton donor/acceptor => ECO:0000305|PubMed:11173464, ECO:0000305|PubMed:11316882
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
237 |
| type |
ACT_SITE |
| sequence |
K
|
| description |
Proton donor/acceptor => ECO:0000305|PubMed:11173464, ECO:0000305|PubMed:11316882
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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3)
|
chain |
B |
| residue |
12 |
| type |
BINDING |
| sequence |
I
|
| description |
BINDING => ECO:0000269|PubMed:11173464, ECO:0007744|PDB:1DWO
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
B |
| residue |
81 |
| type |
BINDING |
| sequence |
C
|
| description |
BINDING => ECO:0000269|PubMed:11173464, ECO:0007744|PDB:1DWO
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
B |
| residue |
82 |
| type |
BINDING |
| sequence |
A
|
| description |
BINDING => ECO:0000269|PubMed:11173464, ECO:0007744|PDB:1DWO
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
6)
|
chain |
B |
| residue |
209 |
| type |
SITE |
| sequence |
K
|
| description |
Increases basicity of active site His => ECO:0000305|PubMed:11316882
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|