eF-site ID 1dsz-B PDB Code 1dsz Chain B click to enlarge Title STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER IN COMPLEX WITH THE RETINOIC ACID RESPONSE ELEMENT DR1 Classification TRANSCRIPTION/DNA Compound DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3') Source Homo sapiens (Human) (1DSZ) Sequence B:  GSFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDL TYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQE ERQR Description Functional site 1) chain B residue 1235 type sequence C description BINDING SITE FOR RESIDUE ZN B 1221 source : AC3 2) chain B residue 1238 type sequence C description BINDING SITE FOR RESIDUE ZN B 1221 source : AC3 3) chain B residue 1252 type sequence C description BINDING SITE FOR RESIDUE ZN B 1221 source : AC3 4) chain B residue 1255 type sequence C description BINDING SITE FOR RESIDUE ZN B 1221 source : AC3 5) chain B residue 1271 type sequence C description BINDING SITE FOR RESIDUE ZN B 1222 source : AC4 6) chain B residue 1277 type sequence C description BINDING SITE FOR RESIDUE ZN B 1222 source : AC4 7) chain B residue 1287 type sequence C description BINDING SITE FOR RESIDUE ZN B 1222 source : AC4 8) chain B residue 1290 type sequence C description BINDING SITE FOR RESIDUE ZN B 1222 source : AC4 9) chain B residue 1235 type BINDING sequence C description BINDING => ECO:0000269|PubMed:10669605, ECO:0007744|PDB:1BY4 source Swiss-Prot : SWS_FT_FI3 10) chain B residue 1238 type BINDING sequence C description BINDING => ECO:0000269|PubMed:10669605, ECO:0007744|PDB:1BY4 source Swiss-Prot : SWS_FT_FI3 11) chain B residue 1252 type BINDING sequence C description BINDING => ECO:0000269|PubMed:10669605, ECO:0007744|PDB:1BY4 source Swiss-Prot : SWS_FT_FI3 12) chain B residue 1255 type BINDING sequence C description BINDING => ECO:0000269|PubMed:10669605, ECO:0007744|PDB:1BY4 source Swiss-Prot : SWS_FT_FI3 13) chain B residue 1271 type BINDING sequence C description BINDING => ECO:0000269|PubMed:10669605, ECO:0007744|PDB:1BY4 source Swiss-Prot : SWS_FT_FI3 14) chain B residue 1277 type BINDING sequence C description BINDING => ECO:0000269|PubMed:10669605, ECO:0007744|PDB:1BY4 source Swiss-Prot : SWS_FT_FI3 15) chain B residue 1287 type BINDING sequence C description BINDING => ECO:0000269|PubMed:10669605, ECO:0007744|PDB:1BY4 source Swiss-Prot : SWS_FT_FI3 16) chain B residue 1290 type BINDING sequence C description BINDING => ECO:0000269|PubMed:10669605, ECO:0007744|PDB:1BY4 source Swiss-Prot : SWS_FT_FI3 17) chain B residue 1235-1300 type DNA_BIND sequence CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDN KDCLIDKRQRNRCQYCRYQKCLAMGM description Nuclear receptor => ECO:0000255|PROSITE-ProRule:PRU00407 source Swiss-Prot : SWS_FT_FI1 18) chain B residue 1235-1255 type ZN_FING sequence CAICGDRSSGKHYGVYSCEGC description NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407 source Swiss-Prot : SWS_FT_FI2 19) chain B residue 1271-1295 type ZN_FING sequence CRDNKDCLIDKRQRNRCQYCRYQKC description NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407 source Swiss-Prot : SWS_FT_FI2 20) chain B residue 1229 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI4 21) chain B residue 1245 type MOD_RES sequence K description N6-acetyllysine; by EP300 => ECO:0000269|PubMed:17761950 source Swiss-Prot : SWS_FT_FI5 22) chain B residue 1235-1261 type prosite sequence CAICGDRSSGKHYGVYSCEGCKGFFKR description NUCLEAR_REC_DBD_1 Nuclear hormones receptors DNA-binding region signature. CfvCq.Dkssgy.HYgvsaCegCkgFFrR source prosite : PS00031

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