eF-site ID 1dqn-AB PDB Code 1dqn Chain A, B click to enlarge Title CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH A TRANSITION STATE ANALOGUE Classification TRANSFERASE Compound GUANINE PHOSPHORIBOSYLTRANSFERASE Source (Q24973_GIALA) Sequence A:  MICSVTGKPVKDVLSTFFKDRNDVLESEVKKFHLLATFEE CKALAADTARRMNEYYKDVAEPVTLVALLTGAYLYASLLT VHLTFPYTLHFVKVSSYKGTRQESVVFDEEDLKQLKEKRE VVLIDEYVDSGHTIFSIQEQIKHAKICSCFVKDVDAIKKH SALADTKMFYGYTPMPKGSWLIGFGLDDNGLRRGWAHLFD INLSESEVTEFRRRLTEHIKGLNINGVNRY B:  MICSVTGKPVKDVLSTFFKDRNDVLESEVKKFHLLATFEE CKALAADTARRMNEYYKDVAEPVTLVALLTGAYLYASLLT VHLTFPYTLHFVKVSSYKGTRQESVVFDEEDLKQLKEKRE VVLIDEYVDSGHTIFSIQEQIKHAKICSCFVKDVDAIKKH SALADTKMFYGYTPMPKGSWLIGFGLDDNGLRRGWAHLFD INLSESEVTEFRRRLTEHIKGLNINGVNRY Description Functional site 1) chain A residue 125 type sequence D description BINDING SITE FOR RESIDUE MG A 450 source : AC1 2) chain A residue 126 type sequence E description BINDING SITE FOR RESIDUE MG A 450 source : AC1 3) chain A residue 187 type sequence D description BINDING SITE FOR RESIDUE MG A 451 source : AC2 4) chain A residue 125 type sequence D description BINDING SITE FOR RESIDUE IMU A 300 source : AC3 5) chain A residue 126 type sequence E description BINDING SITE FOR RESIDUE IMU A 300 source : AC3 6) chain A residue 127 type sequence Y description BINDING SITE FOR RESIDUE IMU A 300 source : AC3 7) chain A residue 129 type sequence D description BINDING SITE FOR RESIDUE IMU A 300 source : AC3 8) chain A residue 130 type sequence S description BINDING SITE FOR RESIDUE IMU A 300 source : AC3 9) chain A residue 131 type sequence G description BINDING SITE FOR RESIDUE IMU A 300 source : AC3 10) chain A residue 132 type sequence H description BINDING SITE FOR RESIDUE IMU A 300 source : AC3 11) chain A residue 133 type sequence T description BINDING SITE FOR RESIDUE IMU A 300 source : AC3 12) chain A residue 180 type sequence W description BINDING SITE FOR RESIDUE IMU A 300 source : AC3 13) chain A residue 181 type sequence L description BINDING SITE FOR RESIDUE IMU A 300 source : AC3 14) chain A residue 187 type sequence D description BINDING SITE FOR RESIDUE IMU A 300 source : AC3 15) chain A residue 69 type sequence L description BINDING SITE FOR RESIDUE POP A 400 source : AC4 16) chain A residue 70 type sequence T description BINDING SITE FOR RESIDUE POP A 400 source : AC4 17) chain A residue 71 type sequence G description BINDING SITE FOR RESIDUE POP A 400 source : AC4 18) chain A residue 187 type sequence D description BINDING SITE FOR RESIDUE POP A 400 source : AC4 19) chain A residue 193 type sequence R description BINDING SITE FOR RESIDUE POP A 400 source : AC4 20) chain B residue 125 type sequence D description BINDING SITE FOR RESIDUE IMU B 301 source : AC5 21) chain B residue 126 type sequence E description BINDING SITE FOR RESIDUE IMU B 301 source : AC5 22) chain B residue 127 type sequence Y description BINDING SITE FOR RESIDUE IMU B 301 source : AC5 23) chain B residue 129 type sequence D description BINDING SITE FOR RESIDUE IMU B 301 source : AC5 24) chain B residue 130 type sequence S description BINDING SITE FOR RESIDUE IMU B 301 source : AC5 25) chain B residue 131 type sequence G description BINDING SITE FOR RESIDUE IMU B 301 source : AC5 26) chain B residue 132 type sequence H description BINDING SITE FOR RESIDUE IMU B 301 source : AC5 27) chain B residue 133 type sequence T description BINDING SITE FOR RESIDUE IMU B 301 source : AC5 28) chain B residue 180 type sequence W description BINDING SITE FOR RESIDUE IMU B 301 source : AC5 29) chain B residue 181 type sequence L description BINDING SITE FOR RESIDUE IMU B 301 source : AC5 30) chain B residue 186 type sequence L description BINDING SITE FOR RESIDUE IMU B 301 source : AC5 31) chain B residue 187 type sequence D description BINDING SITE FOR RESIDUE IMU B 301 source : AC5 32) chain B residue 69 type sequence L description BINDING SITE FOR RESIDUE POP B 401 source : AC6 33) chain B residue 70 type sequence T description BINDING SITE FOR RESIDUE POP B 401 source : AC6 34) chain B residue 71 type sequence G description BINDING SITE FOR RESIDUE POP B 401 source : AC6 35) chain B residue 187 type sequence D description BINDING SITE FOR RESIDUE POP B 401 source : AC6 36) chain B residue 193 type sequence R description BINDING SITE FOR RESIDUE POP B 401 source : AC6 37) chain B residue 18 type sequence F description BINDING SITE FOR RESIDUE IPA B 500 source : AC7 38) chain B residue 20 type sequence D description BINDING SITE FOR RESIDUE IPA B 500 source : AC7 39) chain B residue 21 type sequence R description BINDING SITE FOR RESIDUE IPA B 500 source : AC7 40) chain B residue 24 type sequence V description BINDING SITE FOR RESIDUE IPA B 500 source : AC7 41) chain B residue 29 type sequence V description BINDING SITE FOR RESIDUE IPA B 500 source : AC7 42) chain B residue 100 type sequence T description BINDING SITE FOR RESIDUE IPA B 500 source : AC7

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