|
|
eF-site ID
|
1dm4-B |
|
PDB Code
|
1dm4 |
|
Chain
|
B |
|
click to enlarge
|
|
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Title
|
SER195ALA MUTANT OF HUMAN THROMBIN COMPLEXED WITH FIBRINOPEPTIDE A (7-16) |
|
Classification
|
HYDROLASE |
|
Compound
|
PROTEIN (ALPHA THROMBIN:LIGHT CHAIN) |
|
Source
|
Homo sapiens (Human) (1DM4) |
|
|
Sequence
|
B: |
IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLT
AAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISM
LEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL
PDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPI
VERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGG
PFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLK
KWIQKVIDQFGE
|
|
|
Description
|
(1) |
SER195ALA MUTANT OF HUMAN THROMBIN COMPLEXED WITH FIBRINOPEPTIDE A (7-16)
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
102 |
| type |
SITE |
| sequence |
D
|
| description |
Cleavage; by thrombin; to release fibrinopeptide A
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
195 |
| type |
SITE |
| sequence |
A
|
| description |
Cleavage; by thrombin; to release fibrinopeptide A
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
60 |
| type |
CARBOHYD |
| sequence |
L
|
| description |
N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19838169, ECO:0000269|PubMed:873923
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
B |
| residue |
53-58 |
| type |
prosite |
| sequence |
LTAAHC
|
| description |
TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC
|
| source |
prosite : PS00134
|
|
|
|