eF-site ID 1dl2-A PDB Code 1dl2 Chain A click to enlarge Title CRYSTAL STRUCTURE OF CLASS I ALPHA-1,2-MANNOSIDASE FROM SACCHAROMYCES CEREVISIAE AT 1.54 ANGSTROM RESOLUTION Classification HYDROLASE Compound CLASS I ALPHA-1,2-MANNOSIDASE Source (MNS1_YEAST) Sequence A:  GAGEMRDRIESMFLESWRDYSKHGWGYDVYGPIEHTSHNM PRGNQPLGWIIVDSVDTLMLMYNSSTLYKSEFEAEIQRSE HWINDVLDFDIDAEVNVFETTIRMLGGLLSAYHLSDVLEV GNKTVYLNKAIDLGDRLALAFLSTQTGIPYSSINLHSGQA VKNHADGGASSTAEFTTLQMEFKYLAYLTGNRTYWELVER VYEPLYKNNDLLNTYDGLVPIYTFPDTGKFGASTIRFGSR GDSFYEYLLKQYLLTHETLYYDLYRKSMEGMKKHLLAQSK PSSLWYIGEREQGLHGQLSPKMDHLVCFMGGLLASGSTEG LSIHEARRRPFFSKSDWDLAKGITDTCYQMYKQSSSGLAP EIVVFNDGNIKDGWWRSSVGDFFVKPLDRHNLQRPETVES IMFMYHLSHDHKYREWGAEIATSFFENTCVDCNDPKLRRF TSLSDCITLPTKKSNNMESFWLAETLKYLYILFLDEFDLT KVVFNTEAHPFPVLDEEILKSQSLTTGWSL Description (1)  CLASS I ALPHA-1,2-MANNOSIDASE (E.C.3.2.1.113) Functional site 1) chain A residue 132 type catalytic sequence E description 19 source MCSA : MCSA1 2) chain A residue 136 type catalytic sequence R description 19 source MCSA : MCSA1 3) chain A residue 275 type catalytic sequence D description 19 source MCSA : MCSA1 4) chain A residue 435 type catalytic sequence E description 19 source MCSA : MCSA1 5) chain A residue 399 type ACT_SITE sequence E description Proton donor => ECO:0000250|UniProtKB:P31723 source Swiss-Prot : SWS_FT_FI1 6) chain A residue 96 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|Ref.7, ECO:0007744|PDB:1G6I source Swiss-Prot : SWS_FT_FI3 7) chain A residue 155 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|Ref.7, ECO:0007744|PDB:1G6I source Swiss-Prot : SWS_FT_FI3 8) chain A residue 224 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|Ref.7, ECO:0007744|PDB:1G6I source Swiss-Prot : SWS_FT_FI3 9) chain A residue 525 type BINDING sequence T description BINDING => ECO:0000269|PubMed:10675327 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links