eF-site ID 1dkw-A
PDB Code 1dkw
Chain A

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Title CRYSTAL STRUCTURE OF TRIOSE-PHOSPHATE ISOMERASE WITH MODIFIED SUBSTRATE BINDING SITE
Classification ISOMERASE
Compound TRIOSEPHOSPHATE ISOMERASE
Source Trypanosoma brucei brucei (TPIS_TRYBB)
Sequence A:  SKPQPIAAANWKSGSPDSLSELIDLFNSTSINHDVQCVVA
STFVHLAMTKERLSHPKFVIAAQNAGNEDSLPSLKDFGVN
WIVLGHSERRWYYGETNEIVADKVAAAVASGFMVIACIGE
TLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPV
WAIGTGKVATPQQAQEAHALIRSWVSSKIGADVAGELRIL
YGGSVNGKNARTLYQQRDVNGFLVGLKPEFVDIIKATQ
Description


Functional site

1) chain A
residue 103
type ACT_SITE
sequence G
description Electrophile
source Swiss-Prot : SWS_FT_FI1

2) chain A
residue 175
type ACT_SITE
sequence G
description Proton acceptor
source Swiss-Prot : SWS_FT_FI2

3) chain A
residue 11
type BINDING
sequence N
description
source Swiss-Prot : SWS_FT_FI3

4) chain A
residue 13
type BINDING
sequence K
description
source Swiss-Prot : SWS_FT_FI3

5) chain A
residue 165-175
type prosite
sequence AYEPVWAIGTG
description TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG
source prosite : PS00171


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