eF-site ID 1dfp-A PDB Code 1dfp Chain A click to enlarge Title FACTOR D INHIBITED BY DIISOPROPYL FLUOROPHOSPHATE Classification SERINE PROTEASE Compound FACTOR D Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; Sequence A:  ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAA HCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPD SQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPG TLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHH DGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSG SRVCGNRKKPGIYTRVASYAAWIDSVLA Description Functional site 1) chain A residue 192 type sequence K description BINDING SITE FOR RESIDUE DFP A 500 source : AC1 2) chain A residue 193 type sequence G description BINDING SITE FOR RESIDUE DFP A 500 source : AC1 3) chain A residue 195 type sequence S description BINDING SITE FOR RESIDUE DFP A 500 source : AC1 4) chain A residue 214 type sequence T description BINDING SITE FOR RESIDUE DFP A 500 source : AC1 5) chain A residue 215 type sequence S description BINDING SITE FOR RESIDUE DFP A 500 source : AC1 6) chain A residue 216 type sequence G description BINDING SITE FOR RESIDUE DFP A 500 source : AC1 7) chain A residue 57 type ACT_SITE sequence H description Charge relay system source Swiss-Prot : SWS_FT_FI1 8) chain A residue 102 type ACT_SITE sequence D description Charge relay system source Swiss-Prot : SWS_FT_FI1 9) chain A residue 195 type ACT_SITE sequence S description Charge relay system source Swiss-Prot : SWS_FT_FI1 10) chain A residue 53-58 type prosite sequence LSAAHC description TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LSAAHC source prosite : PS00134 11) chain A residue 189-200 type prosite sequence DSCKGDSGGPLV description TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPLV source prosite : PS00135

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