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eF-site ID
|
1dfb-HL |
|
PDB Code
|
1dfb |
|
Chain
|
H, L |
|
click to enlarge
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Title
|
STRUCTURE OF A HUMAN MONOCLONAL ANTIBODY FAB FRAGMENT AGAINST GP41 OF HUMAN IMMUNODEFICIENCY VIRUS TYPE I |
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Classification
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IMMUNOGLOBULIN |
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Compound
|
IGG1-KAPPA 3D6 FAB (LIGHT CHAIN) |
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Source
|
(GC1_HUMAN) |
|
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Sequence
|
H: |
EVQLVESGGGLVQPGRSLRLSCAASGFTFNDYAMHWVRQA
PGKGLEWVSGISWDSSSIGYADSVKGRFTISRDNAKNSLY
LQMNSLRAEDMALYYCVKGRDYYDSGGYFTVAFDIWGQGT
MVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFP
EPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSS
SLGTQTYICNVNHKPSNTKVDKKVEPKSC
|
| L: |
DIQMTQSPSTLSASVGDRVTITCRASQSISRWLAWYQQKP
GKVPKLLIYKASSLESGVPSRFSGSGSGTEFTLTISSLQP
DDFATYYCQQYNSYSFGPGTKVDIKRTVAAPSVFIFPPSD
EQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQES
VTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLS
SPVTKSFNRGEC
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Description
|
(1) |
3D6 FAB
|
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Functional site
|
|
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1)
|
chain |
L |
| residue |
190-196 |
| type |
prosite |
| sequence |
YACEVTH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
|
| source |
prosite : PS00290
|
|
|
2)
|
chain |
H |
| residue |
207-213 |
| type |
prosite |
| sequence |
YICNVNH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
|
| source |
prosite : PS00290
|
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