eF-site ID 1d5x-A PDB Code 1d5x Chain A click to enlarge Title X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH DIPEPTIDE MIMETIC AND SEB Classification IMMUNE SYSTEM/PEPTIDE INHIBITOR Compound HLA CLASS II HISTOCOMPATIBILITY ANTIGEN Source ORGANISM_SCIENTIFIC: Staphylococcus aureus; Sequence A:  EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETV WRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPI TNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWL RNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYD CRVEHWGLDEPLLKHWEFD Description Functional site 1) chain A residue 9 type sequence Q description BINDING SITE FOR CHAIN D OF DIPEPTIDE MIMETIC INHIBITOR source : AC1 2) chain A residue 11 type sequence E description BINDING SITE FOR CHAIN D OF DIPEPTIDE MIMETIC INHIBITOR source : AC1 3) chain A residue 32 type sequence F description BINDING SITE FOR CHAIN D OF DIPEPTIDE MIMETIC INHIBITOR source : AC1 4) chain A residue 53 type sequence S description BINDING SITE FOR CHAIN D OF DIPEPTIDE MIMETIC INHIBITOR source : AC1 5) chain A residue 54 type sequence F description BINDING SITE FOR CHAIN D OF DIPEPTIDE MIMETIC INHIBITOR source : AC1 6) chain A residue 62 type sequence N description BINDING SITE FOR CHAIN D OF DIPEPTIDE MIMETIC INHIBITOR source : AC1 7) chain A residue 65 type sequence V description BINDING SITE FOR CHAIN D OF DIPEPTIDE MIMETIC INHIBITOR source : AC1 8) chain A residue 172 type sequence E description BINDING SITE FOR CHAIN D OF DIPEPTIDE MIMETIC INHIBITOR source : AC1 9) chain A residue 55 type SITE sequence E description Pathogen-derived peptide antigen => ECO:0000269|PubMed:23260142, ECO:0007744|PDB:4GBX source Swiss-Prot : SWS_FT_FI5 10) chain A residue 62 type SITE sequence N description Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX source Swiss-Prot : SWS_FT_FI6 11) chain A residue 69 type SITE sequence N description Pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX source Swiss-Prot : SWS_FT_FI7 12) chain A residue 76 type SITE sequence R description Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX source Swiss-Prot : SWS_FT_FI8 13) chain A residue 78 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400 source Swiss-Prot : SWS_FT_FI9 14) chain A residue 118 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400 source Swiss-Prot : SWS_FT_FI9 15) chain A residue 52 type BINDING sequence A description BINDING => ECO:0000269|PubMed:8145819 source Swiss-Prot : SWS_FT_FI2 16) chain A residue 53 type SITE sequence S description Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819 source Swiss-Prot : SWS_FT_FI4 17) chain A residue 161-167 type prosite sequence YDCRVEH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YDCRVEH source prosite : PS00290

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