|
|
eF-site ID
|
1cz8-V |
|
PDB Code
|
1cz8 |
|
Chain
|
V |
|
click to enlarge
|
|
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Title
|
VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH AN AFFINITY MATURED ANTIBODY |
|
Classification
|
IMMUNE SYSTEM |
|
Compound
|
Vascular endothelial growth factor A |
|
Source
|
Homo sapiens (Human) (1CZ8) |
|
|
Sequence
|
V: |
VVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVP
LMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGE
MSFLQHNKCECRPK
|
|
|
Description
|
(1) |
VASCULAR ENDOTHELIAL GROWTH FACTOR/LIGHT CHAIN OF NEUTRALIZING ANTIBODY/HEAVY CHAIN OF NEUTRALIZING ANTIBODY COMPLEX
|
|
Functional site
|
|
|
1)
|
chain |
V |
| residue |
91 |
| type |
|
| sequence |
I
|
| description |
BINDING SITE FOR RESIDUE SO4 Y 301
|
| source |
: AC2
|
|
|
2)
|
chain |
V |
| residue |
49-61 |
| type |
prosite |
| sequence |
PSCVPLMRCGGCC
|
| description |
PDGF_1 Platelet-derived growth factor (PDGF) family signature. PSCVplmRCGGCC
|
| source |
prosite : PS00249
|
|
|
|