eF-site ID 1cyn-A PDB Code 1cyn Chain A click to enlarge Title CYCLOPHILIN B COMPLEXED WITH [D-(CHOLINYLESTER)SER8]-CYCLOSPORIN Classification ISOMERASE/IMMUNOSUPPRESSANT Compound PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B Source (NOR00033) Sequence A:  GPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVA LATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSI YGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVK TAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVI IADCGKIEVEKPFAIAKE Description (1)  PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B (E.C.5.2.1.8), CYCLOSPORIN A Functional site 1) chain A residue 63 type sequence R description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 2) chain A residue 68 type sequence F description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 3) chain A residue 71 type sequence Q description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 4) chain A residue 80 type sequence G description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 5) chain A residue 109 type sequence A description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 6) chain A residue 110 type sequence N description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 7) chain A residue 111 type sequence A description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 8) chain A residue 119 type sequence Q description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 9) chain A residue 121 type sequence F description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 10) chain A residue 129 type sequence W description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 11) chain A residue 134 type sequence H description BINDING SITE FOR CHAIN C OF CYCLOSPORIN A source : AC1 12) chain A residue 56-73 type prosite sequence YKNSKFHRVIKDFMIQGG description CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YknSkFHRVIkdFMiQGG source prosite : PS00170 13) chain A residue 60 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:Q99KR7 source Swiss-Prot : SWS_FT_FI1 14) chain A residue 141 type MOD_RES sequence L description N6-acetyllysine => ECO:0000250|UniProtKB:Q99KR7 source Swiss-Prot : SWS_FT_FI2 15) chain A residue 178 type MOD_RES sequence P description S-nitrosocysteine => ECO:0000250|UniProtKB:Q99KR7 source Swiss-Prot : SWS_FT_FI3 16) chain A residue 124 type CARBOHYD sequence T description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI4

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