eF-site ID 1csg-A
PDB Code 1csg
Chain A

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Title Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor
Classification CYTOKINE
Compound Granulocyte-macrophage colony-stimulating factor
Source Homo sapiens (Human) (CSF2_HUMAN)
Sequence A:  SPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETVEVIS
EMFDLQEPTCLQTRLELYKQGLRGSLTKLKGPLTMMASHY
KQHCPPTPETSCATQIITFESFKENLKDFLLVIPFDCWEP
Description (1)  GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF)


Functional site

1) chain A
residue 88-96
type prosite
sequence CPPTPETSC
description GM_CSF Granulocyte-macrophage colony-stimulating factor signature. CPPTpETsC
source prosite : PS00702

2) chain A
residue 27
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine
source Swiss-Prot : SWS_FT_FI3

3) chain A
residue 37
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine
source Swiss-Prot : SWS_FT_FI3

4) chain A
residue 5
type CARBOHYD
sequence S
description O-linked (GalNAc...) serine => ECO:0000269|PubMed:1737041
source Swiss-Prot : SWS_FT_FI1

5) chain A
residue 7
type CARBOHYD
sequence S
description O-linked (GalNAc...) serine => ECO:0000269|PubMed:1737041
source Swiss-Prot : SWS_FT_FI1

6) chain A
residue 9
type CARBOHYD
sequence S
description O-linked (GalNAc...) serine => ECO:0000269|PubMed:1737041
source Swiss-Prot : SWS_FT_FI1

7) chain A
residue 10
type CARBOHYD
sequence T
description O-linked (GalNAc...) threonine; partial => ECO:0000269|PubMed:1737041
source Swiss-Prot : SWS_FT_FI2


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