|
|
eF-site ID
|
1cmx-A |
|
PDB Code
|
1cmx |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
STRUCTURAL BASIS FOR THE SPECIFICITY OF UBIQUITIN C-TERMINAL HYDROLASES |
|
Classification
|
HYDROLASE |
|
Compound
|
PROTEIN (UBIQUITIN YUH1-UBAL) |
|
Source
|
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (UBIQ_HUMANX) |
|
|
Sequence
|
A: |
RAVVPIESNPEVFTNFAHKLGLKNEWAYFDIYSLTEPELL
AFLPRPVKAIVLLFPINDVIWFKQSVKNACGLYAILHSLS
NNQSLLEPGSDLDNFLKSQSDTSSSKNRFDDVTTDQFVLN
VIKENVQTFSTGQSEAPEATADTNLHYITYVEENGGIFEL
DGRNLSGPLYLGKSDPTATDLIEQELVRVRVASYMENANE
EDVLNFAMLGLGPN
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
90 |
| type |
|
| sequence |
C
|
| description |
CYSTEINE PROTEASE
|
| source |
: CAT
|
|
|
2)
|
chain |
A |
| residue |
166 |
| type |
|
| sequence |
H
|
| description |
CYSTEINE PROTEASE
|
| source |
: CAT
|
|
|
3)
|
chain |
A |
| residue |
181 |
| type |
|
| sequence |
D
|
| description |
CYSTEINE PROTEASE
|
| source |
: CAT
|
|
|
4)
|
chain |
A |
| residue |
181 |
| type |
CROSSLNK |
| sequence |
D
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
5)
|
chain |
A |
| residue |
84-100 |
| type |
prosite |
| sequence |
QSVKNACGLYAILHSLS
|
| description |
UCH_1 Ubiquitin carboxyl-terminal hydrolase family 1 cysteine active-site. QsvkNACGlyaILHSLS
|
| source |
prosite : PS00140
|
|
|
|