eF-site ID 1cmv-A
PDB Code 1cmv
Chain A

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Title HUMAN CYTOMEGALOVIRUS PROTEASE
Classification SERINE PROTEASE
Compound HUMAN CYTOMEGALOVIRUS PROTEASE
Source Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) (VP40_HCMVA)
Sequence A:  APVYVGGFLARYDQSPDLPRDVVEHWALPLNINHDDTAVV
GHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSR
GPVSPLQPDKVVEFLSGSYAGLSLSPFKHVALCSVGRRRG
TLAVYGRDPEWVTQRFPDLTAADRDGLRAQWGDPFRSDSY
GLLGNSVDALYIRERLPKLRYDKQLVGVTERESYVKA
Description


Functional site

1) chain A
residue 132
type
sequence S
description CATALYTIC SITE FOR CHAIN A.
source : ACA

2) chain A
residue 63
type
sequence H
description CATALYTIC SITE FOR CHAIN A.
source : ACA

3) chain A
residue 157
type
sequence H
description CATALYTIC SITE FOR CHAIN A.
source : ACA

4) chain A
residue 63
type ACT_SITE
sequence H
description Charge relay system => ECO:0000255|HAMAP-Rule:MF_04008
source Swiss-Prot : SWS_FT_FI1

5) chain A
residue 132
type ACT_SITE
sequence S
description Charge relay system => ECO:0000255|HAMAP-Rule:MF_04008
source Swiss-Prot : SWS_FT_FI1

6) chain A
residue 157
type ACT_SITE
sequence H
description Charge relay system => ECO:0000255|HAMAP-Rule:MF_04008
source Swiss-Prot : SWS_FT_FI1

7) chain A
residue 256
type SITE
sequence A
description Cleavage; by assemblin; Release site => ECO:0000255|HAMAP-Rule:MF_04008
source Swiss-Prot : SWS_FT_FI2

8) chain A
residue 63
type catalytic
sequence H
description 238
source MCSA : MCSA1

9) chain A
residue 132
type catalytic
sequence S
description 238
source MCSA : MCSA1

10) chain A
residue 134
type catalytic
sequence S
description 238
source MCSA : MCSA1

11) chain A
residue 157
type catalytic
sequence H
description 238
source MCSA : MCSA1

12) chain A
residue 165
type catalytic
sequence R
description 238
source MCSA : MCSA1

13) chain A
residue 166
type catalytic
sequence R
description 238
source MCSA : MCSA1


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