|
|
eF-site ID
|
1cmk-I |
|
PDB Code
|
1cmk |
|
Chain
|
I |
|
click to enlarge
|
|
|
Title
|
CRYSTAL STRUCTURES OF THE MYRISTYLATED CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE REVEAL OPEN AND CLOSED CONFORMATIONS |
|
Classification
|
TRANSFERASE/TRANSFERASE INHIBITOR |
|
Compound
|
cAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT |
|
Source
|
Bos taurus (Bovine) (IPKA_HUMAN) |
|
|
Sequence
|
I: |
TTYADFIASGRTGRRNAIHD
|
|
|
Description
|
(1) |
CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT (E.C.2.7.1.37)
|
|
Functional site
|
|
|
1)
|
chain |
I |
| residue |
3 |
| type |
|
| sequence |
Y
|
| description |
BINDING SITE FOR RESIDUE IOD I 384
|
| source |
: AC1
|
|
|
2)
|
chain |
I |
| residue |
3 |
| type |
|
| sequence |
Y
|
| description |
BINDING SITE FOR RESIDUE IOD I 385
|
| source |
: AC2
|
|
|
3)
|
chain |
I |
| residue |
11 |
| type |
SITE |
| sequence |
R
|
| description |
Important for inhibition => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
I |
| residue |
14 |
| type |
SITE |
| sequence |
R
|
| description |
Important for inhibition => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
I |
| residue |
15 |
| type |
SITE |
| sequence |
R
|
| description |
Important for inhibition => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|