eF-site ID 1ckj-AB PDB Code 1ckj Chain A, B click to enlarge Title CASEIN KINASE I DELTA TRUNCATION MUTANT CONTAINING RESIDUES 1-317 COMPLEX WITH BOUND TUNGSTATE Classification PHOSPHOTRANSFERASE Compound RECOMBINANT CASEIN KINASE I DELTA Source null (KC1D_RAT) Sequence A:  MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLE CVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVM VMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDAR THQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLG YVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQ GFSYDYVFDWNMLKFG B:  MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLE CVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVM VMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDAR THQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLG YVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQ GFSYDYVFDWNML Description Functional site 1) chain A residue 183 type sequence R description BINDING SITE FOR RESIDUE WO4 A 400 source : AC1 2) chain A residue 220 type sequence G description BINDING SITE FOR RESIDUE WO4 A 400 source : AC1 3) chain A residue 229 type sequence K description BINDING SITE FOR RESIDUE WO4 A 400 source : AC1 4) chain A residue 167 type sequence H description BINDING SITE FOR RESIDUE WO4 A 401 source : AC2 5) chain A residue 268 type sequence K description BINDING SITE FOR RESIDUE WO4 A 401 source : AC2 6) chain B residue 183 type sequence R description BINDING SITE FOR RESIDUE WO4 B 400 source : AC3 7) chain B residue 219 type sequence Q description BINDING SITE FOR RESIDUE WO4 B 400 source : AC3 8) chain B residue 220 type sequence G description BINDING SITE FOR RESIDUE WO4 B 400 source : AC3 9) chain B residue 229 type sequence K description BINDING SITE FOR RESIDUE WO4 B 400 source : AC3 10) chain B residue 130 type sequence R description BINDING SITE FOR RESIDUE WO4 B 402 source : AC4 11) chain B residue 159 type sequence K description BINDING SITE FOR RESIDUE WO4 B 402 source : AC4 12) chain A residue 131 type ACT_SITE sequence D description Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10027, ECO:0000269|PubMed:8648628 source Swiss-Prot : SWS_FT_FI1 13) chain B residue 131 type ACT_SITE sequence D description Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10027, ECO:0000269|PubMed:8648628 source Swiss-Prot : SWS_FT_FI1 14) chain A residue 41 type BINDING sequence K description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2 15) chain B residue 18 type BINDING sequence I description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2 16) chain B residue 41 type BINDING sequence K description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2 17) chain A residue 18 type BINDING sequence I description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2 18) chain A residue 18-41 type prosite sequence IGSGSFGDIYLGTDIAAGEEVAIK description PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGSGSFGDIYlGtdiaagee..........VAIK source prosite : PS00107 19) chain A residue 127-139 type prosite sequence FIHRDVKPDNFLM description PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. FiHrDVKpdNFLM source prosite : PS00108

Display surface Download Links