eF-site ID 1cia-A PDB Code 1cia Chain A click to enlarge Title REPLACEMENT OF CATALYTIC HISTIDINE-195 OF CHLORAMPHENICOL ACETYLTRANSFERASE: EVIDENCE FOR A GENERAL BASE ROLE FOR GLUTAMATE Classification TRANSFERASE(ACYLTRANSFERASE) Compound CHLORAMPHENICOL ACETYLTRANSFERASE Source null (CAT3_ECOLI) Sequence A:  MNYTKFDVKNWVRREHFEFYRHRLPCGFSLTSKIDITTLK KSLDDSAYKFYPVMIYLIAQAVNQFDELRMAIKDDELIVW DSVDPQFTVFHQETETFSALSCPYSSDIDQFMVNYLSVME RYKSDTKLFPQGVTPENHLNISALPWVNFDSFNLNVANFT DYFAPIITMAKYQQEGDRLLLPLSVQVHQAVCDGFHVARF INRLQELCNSKLK Description Functional site 1) chain A residue 23 type sequence E description BINDING SITE FOR RESIDUE CO A 222 source : AC1 2) chain A residue 23 type sequence E description BINDING SITE FOR RESIDUE CO A 222 source : AC1 3) chain A residue 27 type sequence H description BINDING SITE FOR RESIDUE CO A 222 source : AC1 4) chain A residue 27 type sequence H description BINDING SITE FOR RESIDUE CO A 222 source : AC1 5) chain A residue 25 type sequence Y description BINDING SITE FOR RESIDUE BME A 536 source : AC3 6) chain A residue 18 type catalytic sequence R description 934 source MCSA : MCSA1 7) chain A residue 174 type catalytic sequence T description 934 source MCSA : MCSA1 8) chain A residue 195 type catalytic sequence Q description 934 source MCSA : MCSA1 9) chain A residue 199 type catalytic sequence D description 934 source MCSA : MCSA1 10) chain A residue 195 type ACT_SITE sequence Q description Proton acceptor source Swiss-Prot : SWS_FT_FI1

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